Elagolix suppresses ovulation in a dose-dependent manner: Results from a 3-month, randomized study in ovulatory women.

CONCLUSION: Women being treated with elagolix may ovulate and should use effective methods of contraception. The rate of ovulation was lowest with elagolix 300 mg BID plus E2/NETA 1/0.5 mg QD. PMID: 31650182 [PubMed - as supplied by publisher]
Source: The Journal of Clinical Endocrinology and Metabolism - Category: Endocrinology Authors: Tags: J Clin Endocrinol Metab Source Type: research

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ConclusionTraditionally only pathologies of the uterus and ovaries are assessed during a routine pelvic ultrasound. Here we demonstrate that the routine ultrasound examination can easily be extended beyond the uterus and ovaries into the posterior and anterior pelvic compartments to evaluate structural mobility and to look for deep infiltrating endometriotic nodules, so women suffering from deep infiltrating endometriosis can benefit from a pre-operative diagnosis and subsequently a single, well-planned procedure in the hands of a well-prepared team.
Source: Journal of Minimally Invasive Gynecology - Category: OBGYN Source Type: research
ConclusionProgestin therapy with D or N appears to be effective in reducing the size of endometriomas and related symptoms, with a greater effect on symptoms relief and higher tolerability in women treated with D.
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - Category: OBGYN Source Type: research
Abstract OBJECTIVE: To determine whether significant hemoperitoneum could be a precursor of deep pelvic endometriosis METHODS: This was a prospective observational cohort study which was carried out in a dedicated gynecological diagnostic unit over a period of 18 months. We included consecutive pre-menopausal, non-pregnant women who attended with severe acute lower abdominal pain and underwent a pelvic ultrasound examination. Women were triaged for surgical or conservative management depending on the cause of pain and severity of their symptoms. Those who were selected for conservative management were invited for ...
Source: The Ultrasound Review of Obstetrics and Gynecology - Category: Radiology Authors: Tags: Ultrasound Obstet Gynecol Source Type: research
We report a case of a 37-year-old woman with abdominal wall endometriosis 11 years after cesarean section. She had low abdominal pain related to menstrual cycle, which intensified at the end of menstrual bleeding. A nodule painful to palpation was found in the medial part of previous Pfannenstiel incision. Ultrasound guided biopsy was performed and the diagnosis of endometriosis confirmed. Surgery is the treatment of choice for abdominal wall endometriosis. Excision with histologically proven free surgical margins of 1 cm is mandatory to prevent recurrence. A wide spectrum of mimicking conditions is the main reason for lat...
Source: Acta Clinica Croatica - Category: General Medicine Tags: Acta Clin Croat Source Type: research
AbstractWhile endometriosis typically affects the ovaries, deep infiltrating endometriosis can affect the gastrointestinal tract, urinary tract, and deep pelvis, awareness of which is important for radiologists. Symptoms are nonspecific and can range from chronic abdominal and deep pelvic pain to nausea, vomiting, diarrhea, constipation, hematuria, and rectal bleeding. Ultrasound and computed tomography may show nonspecific soft-tissue density masses causing bowel obstruction and hydronephrosis. This constellation of presenting symptoms and imaging evidence is easily mistaken for other pathologies including infectious gast...
Source: Abdominal Imaging - Category: Radiology Source Type: research
Conclusions Laparoscopic double discoid resection with circular stapler may be an alternative to segmental bowel resection in selected patients with bowel endometriosis.
Source: Journal of Minimally Invasive Gynecology - Category: OBGYN Source Type: research
The post Ovarian Remnant Syndrome – Sue’s story appeared first on Hysterectomy Association. After suffering with endometriosis I decided at the age of 35 that I wanted a hysterectomy (despite having no children). Since the age of 13 I had suffered with severe period pain. When I was 26 I saw a gynaecologist (Mr W), who decided to do a D&C, this did not help with the pain so Mr W then did a laparoscopy. I was diagnosed with extensive endometriosis. I then began a course of Zoladex injections. At the end of the course I had another laparoscopy and the endometriosis was no more. Was I cured? NO! Three months later...
Source: The Hysterectomy Association - Category: OBGYN Authors: Tags: Your Stories endometriosis ovarian remnant syndrome Source Type: news
Years of bowel disease and endometriosis had left me with a very sticky, complex pelvis. I reached the age of 50 and an MRI indicated I had ovarian cancer. This proved to be incorrect but my consultant was becoming increasingly concerned at the state of my insides and how the suspect masses presented on ultrasound and MRI’s. So much so he recommended a complete hysterectomy as otherwise I would live with this uncertainty for ever. This was four years ago – I was warned the surgery would be complex owing to numerous operations for bowel disease and endometriosis but on the basis the scans was no longer reliable,...
Source: The Hysterectomy Association - Category: OBGYN Authors: Tags: Your Stories endometriosis perforated bowel Source Type: news
​BY MATTHEW​ J. LETIZIA, DO; &JOSEPH V. M. KELLY, MD, MBA ​A 19-year-old woman with no past medical or surgical history presented to the emergency department stating that she had noticed a growth protruding from her vagina. It has been painless except during intercourse and constant in all characterizations since detection three days earlier. She denies vaginal bleeding, urinary retention, incontinence, fever, injury, and back, abdominal, and pelvic pain.​Her vital signs are normal, but her physical examination was significant for a 2.5 cm x 4 cm stalk-like, pedunculated, fluctuant, nontender, mobile, cyst...
Source: The Case Files - Category: Emergency Medicine Tags: Blog Posts Source Type: research
Endometriosis is a benign inflammatory disease defined by the presence of endometrial glands and stroma in areas outside the uterus. It is estimated to affect 5%–15% of women of reproductive age and is even more prevalent among women with chronic pelvic pain and infertility. Endometriotic implants may be located anywhere within the pelvis, including the ovaries, ovarian fossa, pelvic peritoneum, rectovaginal septum, uterosacral ligaments, and cul-de sac. In some cases, ovarian endometriotic cysts (endometriomas) may be observed by ultrasound imaging.
Source: Fertility and Sterility - Category: Reproduction Medicine Authors: Tags: Inklings Source Type: research
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