Effect of an Invasive Strategy on Outcome in Patients ≥75 Years of Age with Non-ST-Elevation Acute Coronary Syndrome

The Italian Elderly ACS study was the first randomized trial (RCT) comparing an early aggressive (EA) with an initially conservative strategy in patients with NSTEACS aged ≥75 years, with the results showing no significant benefit of EA. We evaluated the outcomes of study patients, according to the treatment actually received during hospitalization. The RCT enrolled 313 patients. The primary endpoint was the composite of death, myocardial infarction (MI), disabling stroke, and repeat hospital stay for cardiovascular causes or bleeding within 1 year.

Source: The American Journal of Cardiology - December 17, 2014 Category: Cardiology Authors: Gennaro Galasso, Stefano De Servi, Stefano Savonitto, Teresa Strisciuglio, Raffaele Piccolo, Nuccia Morici, Ernesto Murena, Claudio Cavallini, Anna Sonia Petronio, Federico Piscione Source Type: research