9p21.3 Coronary Artery Disease Risk Locus and Interferon Alpha 21: Association study in an Asian Indian population

ConclusionsIFNA21 may be involved in inflammatory processes in an age dependent manner and in progression of CAD. This IFNA21 mediated mechanism may be more active in females. Several 9p21 SNPs may modulate inflammatory processes mediated by IFNA21, and may therefore contribute to pathophysiology of CAD.
Source: Indian Heart Journal - Category: Cardiology Source Type: research