High incidence of heparin-induced allergic delayed-type hypersensitivity reactions in pregnancy
Conclusions: Among patients receiving long-term heparin anticoagulation during pregnancy, heparin-induced skin lesions are frequent (incidence, 19.8%) and are all caused by allergic DTH reactions. Nadroparin has the highest frequency of skin lesions (approximately 65% at 100 days), which is significantly higher than that of dalteparin (HR, 26.7). Therefore nadroparin use should be avoided in pregnancy when possible.
Source: Journal of Allergy and Clinical Immunology - Category: Allergy & Immunology Authors: Marc Schindewolf, Corinna Gobst, Hartmut Kroll, Andreas Recke, Frank Louwen, Manfred Wolter, Roland Kaufmann, Wolf-Henning Boehncke, Edelgard Lindhoff-Last, Ralf J. Ludwig Tags: Food, drug, insect sting allergy, and anaphylaxis Source Type: research
More News: Allergy | Allergy & Immunology | Anaphylactic Shock | Bleeding | Insect Bites & Stings | Laboratory Medicine | Lovenox | Pregnancy | Skin | Skin Biopsy | Study | Thrombocytopenia | Thrombosis | Women