Detection of Pan drug resistance OXA-48 producing Providencia in an ICU patient for the first time in Nepal

ConclusionsCarbapenamase production along with intrinsic colistin resistance in infecting bacterial pathogens can cause fatal outcomes in the resource limited countries like Nepal where new antibiotic combinations ceftazidime+ Avibactam, or aztreonam +avibactam are not available. Drug resistance patterns including OXA 48 producer should be characterized in all cases by standard phenotypic methods or by Xpert Carba-R assay and larger studies are required to know the exact burden of OXA 48 producer in Nepal.
Source: Antimicrobial Resistance and Infection Control - Category: Infectious Diseases Source Type: research