David aortic valve-sparing reimplantation versus biological aortic root replacement: a retrospective analysis of 411 patients
This study aimed to compare short- and long-term results for patients undergoing either aortic valve-sparing reimplantation (David) procedure (AVr-D) or biological aortic root replacement (Bentall) procedure (ARr-B-bio) for aortic root pathology.MethodsWe compared outcomes for patients who underwent AVr-D (n = 261) or ARr-B-bio (n = 150) between 2000 and 2015 at our institution. The mean age of patients was 55 ± 13 years and 21.7% (n = 89) were female. ARr-B-bio patients were significantly older than AVr-D patients (58 ± 10 vs 53 ± 15 years,p
Is the true clinical value of high sensitivity troponins as a biomarker of risk? The concept that detection of high-sensitivity troponin "never means nothing". Expert Rev Cardiovasc Ther. 2020 Sep 23;: Authors: Hinton J, Gabara L, Curzen N Abstract INTRODUCTION: High sensitivity troponin (hs-cTn) assays are central to the diagnosis of myocardial infarction (MI). Their increased sensitivity has facilitated rapid pathways for the exclusion of MI. However, hs-cTn is now more readily detectable in patients without symptoms typical of MI, in whom a degree of myocardial injury is assumed. Recently,...
We present this case as an example of a rare, but potentially life-threatening, complication of adalimumab. PMID: 32966141 [PubMed - as supplied by publisher]
Publication date: Available online 23 September 2020Source: Preventive Veterinary MedicineAuthor(s): Russell Daly, K.C. Willis, Janet Wood, Kayla Brown, Dustin Brown, Theresa Beguin-Strong, Rockie Smith, Haley Ruesch
Authors: Wang Y, Zhao C, Huang D, Sun B, Wang Z Abstract Cerebral venous sinus thrombosis (CVST) is a rare disease associated with high disability and mortality rates. A subset of patients do not respond to standard anticoagulation therapy, leading to the progression of CVST with hemorrhagic stroke, which represents a major challenge for its treatment. Severe hemorrhagic (SH)-CVST is life-threatening due to large hematoma, edema and/or cerebral hernia. Anticoagulation or thrombolytic therapy alone may lead to further aggravation of the hematoma. Stent retriever thrombectomy combined with long-term local thrombolysi...
Conclusions. Kidney transplant recipients had excess stroke deaths, particularly at younger ages and women. Preexisting cerebrovascular disease was a potentially modifiable risk factor for stroke death, suggesting further studies of secondary stroke prevention for kidney transplant recipients.
Publication date: Available online 23 September 2020Source: Journal of Thermal BiologyAuthor(s): Mohammad Ashaf-Ud-Doulah, Abdullah Al Mamun, Mohammad Lutfar Rahman, S.M. Majharul Islam, Rayeda Jannat, Mostafa Ali Reza Hossain, Md Shahjahan
Sep 25, 2020. . Sponsored by National Indian Health Board
Chem. Commun., 2020, Accepted Manuscript DOI: 10.1039/D0CC05803C, CommunicationXiaopeng Yang, jun tang, Di Zhang, xiaojing han, Jianfei Liu, Jinsa Li, Yufen Zhao, Yong Ye A probe MITO-TPE was developed for imaging mitochondrial SO2 with good selectivity, high sensitivity, and fast response. Cell imaging indicated that SO2 induced oxidative stress may cause damage to cells... The content of this RSS Feed (c) The Royal Society of Chemistry
This study shows that CA are released from periventricular and subpial regions to the cerebrospinal fluid and are present in the cervical lymph nodes, into which cerebrospinal fluid drains through the meningeal lymphatic system. We also show that CA can be phagocytosed by macrophages. We conclude that CA can act as containers that remove waste products from the brain and may be involved in a mechanism that cleans the brain. Moreover, we postulate that CA may contribute in some autoimmune brain diseases, exporting brain substances that interact with the immune system, and hypothesize that CA may contain brain markers that m...
Conclusions: With appropriate preoperative evaluation and careful surgical planning, a minimally invasive approach to reoperative aortic valve surgery can be performed in a safe and effective manner.