Increased neural connectivity between the hypothalamus and cortical resting-state functional networks in chronic migraine

ConclusionThese data provide evidence for hypothalamic involvement in large-scale reorganisation at the functional-network level in CM and in proportion with the perceived severity of the migraine pain.
Source: Journal of Neurology - Category: Neurology Source Type: research

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Conclusion: PC dimensions are associated with a specific structural and functional neuroanatomical pattern, which is different from the pattern observed when PC is considered as a single score. The involvement of basal ganglia and cerebellum needs further investigation. PMID: 31535584 [PubMed - as supplied by publisher]
Source: The World Journal of Biological Psychiatry - Category: Psychiatry Authors: Tags: World J Biol Psychiatry Source Type: research
ConclusionThe E/M ratio is a useful predictor for the recurrence of CRSwNP in the Chinese population.
Source: International Forum of Allergy and Rhinology - Category: Allergy & Immunology Authors: Tags: ORIGINAL ARTICLE Source Type: research
Publication date: Available online 18 June 2019Source: NeuroImage: ClinicalAuthor(s): Hassan Jassar, Thiago D. Nascimento, Niko Kaciroti, Marcos F. DosSantos, Theodora Danciu, Robert A. Koeppe, Yolanda R. Smith, Marcelo E. Bigal, Frank Porreca, Kenneth L. Casey, Jon-Kar Zubieta, Alexandre F. DaSilvaAbstractObjectiveTo evaluate, in vivo, the impact of ongoing chronic migraine (CM) attacks on the endogenous μ-opioid neurotransmission.BackgroundCM is associated with cognitive-emotional dysfunction. CM is commonly associated with frequent acute medication use, including opioids.MethodsWe scanned 15 migraine patients during ...
Source: NeuroImage: Clinical - Category: Radiology Source Type: research
Conclusion Herpes encephalitis may rule your body but don't allow the infection to take over your brain. Herpes encephalitis is suppressible and so its symptoms if managed with great attention. Antiviral drugs such as Zovirax, acyclovir, Valacyclovir are some of the prominently used drugs in suppressing therapy of herpes infection. You are counseled to see your GP as soon as the very onset of any symptoms described above.You've read Cracking the Herpes Encephalitis Code | Causes, Symptoms and Treatment, originally posted on Pick the Brain | Motivation and Self Improvement. If you've enjoyed this, please visit our site f...
Source: PickTheBrain | Motivation and Self Improvement - Category: Consumer Health News Authors: Tags: health and fitness Herpes Encephalitis symptoms of herpes encephalitis Source Type: blogs
Conclusions: Increased [18F]FDG uptake can be observed on PET in the paraspinal muscles of patients with suspected CSF leak. Our results suggest [18F]FDG PET/MRI is sensitive to abnormalities potentially due to suspected CSF leak, which are not necessarily visible on conventional MRI alone. Additionally, these scans can potentially be used to better localize treatment with epidural blood patch injections that are used to stop the leak. Post-treatment scans in these same patients will be useful in determining whether a decrease in symptoms correlates with a decrease in [18F]FDG tracer uptake. Table 1: Abnormal paraspinal fi...
Source: Journal of Nuclear Medicine - Category: Nuclear Medicine Authors: Tags: Musculoskeletal Source Type: research
AbstractPurposeThe aim of the study is to investigate the relation between paranasal sinus volumes and headache in patients with no other rhinologic causes.MethodsTwo hundred patients with chronic headache and 99 subjects with no headache or facial pain history in the last 6  months were included in the study. Paranasal computed tomography (CT) scans of both patient and control groups were evaluated. Sixty one patients were excluded from the study due to possible rhinogenic headache CT findings such as secretions and contact points. Sinus volume index (SVI) formula cre ated by Barghouth et al. in2002 was used to calcu...
Source: European Archives of Oto-Rhino-Laryngology - Category: ENT & OMF Source Type: research
Rui Yan1, ShiWan Tao1, HaiYan Liu1, Yu Chen1, JiaBo Shi1, YuYin Yang1, RongXin Zhu1, ZhiJian Yao1,2* and Qing Lu3,4*1Department of Psychiatry, The Affiliated Brain Hospital of Nanjing Medical University, Nanjing, China2Nanjing Brain Hospital, Medical School of Nanjing University, Nanjing, China3School of Biological Sciences and Medical Engineering, Southeast University, Nanjing, China4Child Development and Learning Science, Key Laboratory of Ministry of Education, Nanjing, ChinaBackground: Major depressive disorders often involve somatic symptoms and have been found to have fundamental differences from non-somatic depressi...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
We examined the expression of TRPV1 in peripheral tissue and DRG neurons of CPIP model rats and we studied whether CPIP model could induce peripheral sensitization of TRPV1 channel and enhance DRG neuron excitability. Then we examined the therapeutic effects of locally applied TRPV1 specific antagonist AMG9810 on pain responses of CPIP model rats. Lastly, we explored the effects of AMG9810 on DRG neuron hyperexcitability and spinal glial activation induced by CPIP. Our results demonstrate that TRPV1 plays an important role in mediating the behavioral hypersensitivity of CPIP model rats via promoting peripheral nociceptor a...
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
DiscussionAs detailed above, the “elements” in both a classical and a contemporary sense have effects on our mental health and are potentially modifiable aspects that can be harnessed as therapeutic interventions. The most robust interventional evidence currently available shows tentative support for several use of the elements via horticultural and nature-exposure therapy, green exercise/physical activity, sauna and heat therapy, balneotherapy, and breathing exercises. It should be noted that, in many cases, these interventions were not studied in definitive diagnosed psychiatric disorders and thus it is prema...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
Sleep Is Compromised in −12° Head Down Tilt Position Alessa L. Boschert1*, David Elmenhorst2,3, Peter Gauger1, Zhili Li4, Maria T. Garcia-Gutierrez5, Darius Gerlach1, Bernd Johannes1, Jochen Zange1, Andreas Bauer2,6 and Jörn Rittweger1,7 1Department of Muscle and Bone Metabolism, German Aerospace Center (DLR), Institute of Aerospace Medicine, Cologne, Germany 2Forschungszentrum Jülich, Institute of Neuroscience and Medicine (INM-2), Jülich, Germany 3Division of Medical Psychology, University of Bonn, Bonn, Germany 4State Key Laboratory of Space Medicine Fundamentals and Application, China ...
Source: Frontiers in Physiology - Category: Physiology Source Type: research
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