Bone marrow-mesenchymal stem cells modulate microglial activation in the peri-infarct area in rats during the acute phase of stroke.

CONCLUSION: The transplanted BM-MSCs exerted immunomodulatory effect by inactivating the microglias in the peri-infarct area, at least partially, via the CD200-CD200R1 signaling.
PMID: 31589902 [PubMed - as supplied by publisher]

Source: Brain Research Bulletin - October 3, 2019 Category: Neurology Authors: Li Z, Ye H, Cai X, Sun W, He B, Yang Z, Xu P Tags: Brain Res Bull Source Type: research