HIF-1 α/BNIP3 signaling pathway-induced-autophagy plays protective role during myocardial ischemia-reperfusion injury.

CONCLUSIONS: Together, our studies indicated that HIF-1α synchronization regulate BNIP3 during OGD/R injury-induced autophagy in H9C2 cells, though BNIP3-induced autophagy acting as a survival mechanism. PMID: 31590128 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31590128?dopt=Abstract

Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - October 3, 2019 Category: Drugs & Pharmacology Authors: Zhang Y, Liu D, Hu H, Zhang P, Xie R, Cui W Tags: Biomed Pharmacother Source Type: research