Hedgehog signalling network gene status analysis in paediatric intracranial germ cell tumours.

CONCLUSIONS: Our results show few genomic alterations related to the Hh signalling pathway genes in paediatric intracranial GCTs. Further analysis of Hedgehog pathway alterations can potentially disclose its biological significance and define new prognostic factors and/or therapeutic targets for high-risk patients. PMID: 31588709 [PubMed - in process]

https://www.ncbi.nlm.nih.gov/pubmed/31588709?dopt=Abstract

Source: Folia Neuropathologica - October 8, 2019 Category: Neurology Tags: Folia Neuropathol Source Type: research