Clinical Profile of Patients with Acute Intracerebral Hemorrhage and ICH Score as an Outcome Predictor on Discharge, 30 Days and 60 Days Follow-up.

This study was conducted in the Department of Neurology, Government Medical College, Kota, Rajasthan, India from January 2016 to August 2016. 120 consecutive patients presenting with acute ICH were studied. Data collected included demographics, clinical parameters, cranial Computed Tomography(CT) findings and ICH score on presentation. Primary outcome was defined as mortality/morbidity during hospitalisation, on discharge, 30 days and 60 days follow-up. Modified Rankin score (mRS) was used to assess the outcome. Statistical analysis used: SPSS 19 statistical software. Results: Of the total 120 patients with Acute ICH(108 supratentorial and 12 infratentorial) studied, 48(40%) patients died during hospitalisation. Mean age was 66.9 ± 13.5 Years. Hydrocephalus, midline shift and IV extension on presenting CT scan was observed in 20 (16.6%), 44 (36.6%) and 48 (40%)patients respectively. The independent predictors of increased mortality with statistical significance (p
Source: Journal of the Association of Physicians of India - Category: General Medicine Tags: J Assoc Physicians India Source Type: research

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Shanshan Zhang1, Dongli Yuan2 and Ge Tan1* 1Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China 2The Institute of Medical Information, Chongqing Medical University, Chongqing, China Primary systemic vasculitis can affect every structure in both the central and peripheral nervous system, causing varied neurological manifestations of neurological dysfunction. Early recognition of the underlying causes of the neurological symptoms can facilitate timely treatment and improve the prognosis. This review highlights the clinical manifestations of primary systemic vasc...
Source: Frontiers in Neurology - Category: Neurology Source Type: research
Conclusion: We identified a novel non-sense mutation in MTHFR gene in a single Egyptian family with severe MTHFR deficiency. The present investigation is clinically important, as it adds to the growing list of MTHFR mutations, which might help in genetic counseling of families of affected children and proper genotype-phenotype correlation. Background Severe 5,10-Methylenetetrahydrofolate reductase (MTHFR; OMIM 236250) deficiency is a rare inborn error of metabolism and inherited in an autosomal recessive fashion. It is a very common disorder of folate metabolism and is clinically characterized with low plasma methion...
Source: Frontiers in Neurology - Category: Neurology Source Type: research
(The Mount Sinai Hospital / Mount Sinai School of Medicine) An artificial intelligence platform designed to identify a broad range of acute neurological illnesses, such as stroke, hemorrhage, and hydrocephalus, was shown to identify disease in CT scans in 1.2 seconds, faster than human diagnosis.
Source: EurekAlert! - Biology - Category: Biology Source Type: news
AbstractAcute phase after aneurysmal subarachnoid hemorrhage (aSAH) is associated with several metabolic derangements including stress-induced hyperglycemia (SIH). The present study is designed to identify objective radiological determinants for SIH to better understand its contributory role in clinical outcomes after aSAH. A computer-aided detection tool was used to segment admission computed tomography (CT) images of aSAH patients to estimate intracranial blood and cerebrospinal fluid volumes. Modified Graeb score (mGS) was used as a semi-quantitative measure to estimate degree of hydrocephalus. The relationship between ...
Source: Translational Stroke Research - Category: Neurology Source Type: research
Discussion. Pneumocephalus is defined by two mechanisms: a ball-valve and an inverted bottle concept.1 The ball-valve type implies positive pressure events, such as coughing or valsalva maneuvers, that prevent air escape. Tension pneumocephalus is included in this mechanism, causing a parenchymal mass effect. The inverted bottle theory includes a negative intracranial pressure gradient following cerebrospinal fluid drainage, relieved by air influx. A small pneumocephalus is usually sealed by blood clots or granulation, allowing spontaneous reabsorption and resolution.[1] Otherwise, the lateral positioning of a patient duri...
Source: Innovations in Clinical Neuroscience - Category: Neuroscience Authors: Tags: Assessment Tools CNS Infections Current Issue Letters to the Editor Neurologic Systems and Symptoms Neurology Stroke Traumatic Brain Injury epidural needle size Pneumocephalus spinal tap Source Type: research
Conclusions We presented a case of dolichoectasia of vertebrobasilar artery with an obstructive hydrocephalus, due to direct compression on pons and midbrain, which is an extremely rare entity. This case had been analyzed during the patient's life through clinical, laboratory, and radiology examinations and after he died through autopsy.
Source: The American Journal of Forensic Medicine and Pathology - Category: Forensic Medicine Tags: Case Reports Source Type: research
Conclusion: Computed tomography scan has a high diagnostic yield, especially in elderly patients with recurrent generalized seizures. Brain tumors, encephalomalacia, and HCP are most common causes of recurrent seizures in the adults.
Source: Nigerian Journal of Clinical Practice - Category: Rural Health Authors: Source Type: research
Conclusions We presented a case of dolichoectasia of vertebrobasilar artery with an obstructive hydrocephalus, due to direct compression on pons and midbrain, which is an extremely rare entity. This case had been analyzed during the patient's life through clinical, laboratory, and radiology examinations and after he died through autopsy.
Source: The American Journal of Forensic Medicine and Pathology - Category: Forensic Medicine Tags: Case Reports Source Type: research
CONCLUSIONS PTV presents early after NAHT, particularly after a DC has been performed. However, the authors found that only a few PTV/NAHT patients developed shunt-dependent hydrocephalus. PMID: 27798981 [PubMed - in process]
Source: Neurosurgical Focus - Category: Neurosurgery Authors: Tags: Neurosurg Focus Source Type: research
This study reports preliminary data on cognitive outcomes in a prospective cohort of patients with spontaneous SAH who received vasodilator therapy for anterior cerebral artery (ACA) vasospasm.Aim1. Determine role of delayed cerebral ischemia (DCI) and CVS after spontaneous SAH on short-term cognitive outcome.2. Determine if ACA vasospasm predicts short-term cognitive outcome.3. Determine if treatment of ACA vasospasm results in improvement in short-term cognitive outcome.MethodsThirty-five patients with clinical follow-up at 3 months after SAH were selected from a prospective cohort. DCI was defined as a new hypodensity o...
Source: Journal of NeuroInterventional Surgery - Category: Neurosurgery Authors: Tags: Electronic poster abstracts Source Type: research
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