Association between oral iron supplementation and retinal or subretinal hemorrhage in the comparison of age-related macular degeneration treatment trials

Conclusion: Among participants of comparison of age-related macular degeneration treatments trials, the use of oral iron supplements was associated with retinal/subretinal hemorrhage in a dose–response manner. Unindicated iron supplementation may be detrimental in patients with wet age-related macular degeneration.
Source: RETINA - Category: Opthalmology Tags: Original Study Source Type: research

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CONCLUSIONS: Neonatal screening with the red reflex is not sufficient to detect intraocular disease. A normal neonatal red reflex does no exclude intraocular disease. It has a specificity of nearly 90%, but its sensitivity is only 56%. Most retinal haemorrhages are undiagnosed as they cannot be detected with a red reflex. PMID: 31826811 [PubMed - as supplied by publisher]
Source: Archivos de la Sociedad Espanola de Oftalmologia - Category: Opthalmology Tags: Arch Soc Esp Oftalmol Source Type: research
Three medical stories that we didn't cover, explained.Medscape
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Family Medicine/Primary Care News Source Type: news
Publication date: Available online 12 December 2019Source: Pharmacological ResearchAuthor(s): Karan Naresh Amin, Elango Bhakkiyalakshmi, Jayasuriya Ravichandran, D.V.L. Sarada, Ramkumar Kunka MohanramAbstractEndothelial dysfunction (ED) is a key event in the onset and progression of vascular complications associated with diabetes. Regulation of endothelial function and the underlying signaling mechanisms in the progression of diabetes-induced vascular complications have been well established. Recent studies indicate that increased oxidative stress is an important determinant of endothelial injury and patients with hyperten...
Source: Pharmacological Research - Category: Drugs & Pharmacology Source Type: research
Conclusion: This study suggests that all ARB-AML CTs compared favorably to AML monotherapy regarding short-term treatment response in uncomplicated HTN patients of Asian origin. AZL-AML prompted the most favorable treatment response. Safety profiles among the ARB-AML CTs were largely comparable. Due to the limited study size and small number of trials (direct evidence), our findings should best be interpreted as an exploratory effort importance to inform future research direction. PMID: 31827918 [PubMed]
Source: International Journal of Hypertension - Category: Cardiology Tags: Int J Hypertens Source Type: research
Authors: Körösi B, Vecsey-Nagy M, Kolossváry M, Nemcsik-Bencze Z, Szilveszter B, László A, Batta D, Gonda X, Merkely B, Rihmer Z, Maurovich-Horvat P, Eörsi D, Torzsa P, Nemcsik J Abstract Affective temperaments represent a biologically stable core of emotional reactivity and have previously been associated with hypertension and arterial stiffening. The age, when hypertension is initiated, is influenced by different factors, but the role of personality traits in this regard is not clarified yet. Our aim was to study the association between affective temperaments and the age at ons...
Source: International Journal of Hypertension - Category: Cardiology Tags: Int J Hypertens Source Type: research
This study aimed to estimate MetS status and its associations with geography, economic development, birth weight, and parental education of Chinese children and adolescents. METHODS: Data were derived from 15,045 participants aged 7-18 years across seven Chinese provinces. Physical measurement and blood tests were conducted to assess the five classical MetS components described by the International Diabetes Federation, including abdominal obesity (the essential component), high blood pressure, low high-density cholesterol (HDL-C), high triglyceride, and elevated fasting glucose (FG). Logistic regression was adopted to ...
Source: Journal of Atherosclerosis and Thrombosis - Category: Cardiology Tags: J Atheroscler Thromb Source Type: research
Publication date: February 2020Source: Nano Energy, Volume 68Author(s): Binhao Qin, Yuhang Li, Qiao Zhang, Guangxing Yang, Hong Liang, Feng PengAbstractThe electrochemical method is considered being a sustainable alternative to the industrial Haber-Bosch process (150–350 atm, 350–550 °C) because it can produce ammonia (NH3) from nitrogen (N2) and water (H2O) at room temperature and pressure. However, since the N≡N triple bond in N2 is one of the strongest bonds in nature, it requires a more negative potential for N2 reduction, which often leads to violent hydrogen evolution reaction (HER) in...
Source: Nano Energy - Category: Nanotechnology Source Type: research
Publication date: Available online 12 December 2019Source: Journal of Materials Research and TechnologyAuthor(s): C.H. Veloso, L.O. Filippov, I.V. Filippova, S. Ouvrard, A.C. AraujoAbstractThe interactions of polymers (corn starch, dextrin from maize starch, humic acid sodium salt and sodium carboxymethyl cellulose) with iron oxides (hematite and magnetite) have been investigated by measuring adsorption isotherms and by electrophoresis. According to the electrophoresis measurements at pH 7 both iron oxides present negative surface charge and positive at pH 5. The equilibrium adsorption isotherms were then determined at pH ...
Source: Journal of Materials Research and Technology - Category: Materials Science Source Type: research
Publication date: February 2020Source: Carbon, Volume 157Author(s): Ibrahim Abdalla, Ahmed Elhassan, Jianyong Yu, Zhaoling Li, Bin DingAbstractThe quick improvement of up-to-date communication technology has generated ubiquitous electromagnetic wave (EMW), which poses a significant hazard to environment and human health. One of the key challenges associated with EMW is to develop highly lightweight and efficient adsorption materials that are able to alleviate the unfavorable interferences in wide-ranging frequency. Herein, we fabricated a hybrid porous carbon nanofibers (CNFs) membrane combined with reduced graphene oxide ...
Source: Carbon - Category: Materials Science Source Type: research
Publication date: Available online 12 December 2019Source: NeurocomputingAuthor(s): Jiayang Dai, Ning Chen, Biao Luo, Weihua Gui, Chunhua YangAbstractThe iron removal process by goethite is an important part of zinc hydrometallurgy. In existing works, the goethite process is often modelled as a lumped parameter system, where the spatial distribution information of reactants is not involved. In this paper, the spatiotemporal modeling of the goethite process and its optimal control problem are studied. To make the infinite-dimensional distributed parameter system easier to solve, space-time separation is adopted to transform...
Source: Neurocomputing - Category: Neuroscience Source Type: research
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