Fatigue in Multiple Sclerosis is related to relapses, autonomic dysfunctions and introversion: a quasi-experimental study

ConclusionsThis study shows that a relapse is accompanied by an increase in MS-related fatigue. Moreover, autonomic dysfunctions and introversion, more than depression and apathy, play a major role in the explanation of MS-related fatigue. This finding represents additional evidence for the relationship between inflammation, vagal afferent signalling, autonomic dysfunctions, introversion and the feeling of MS-related fatigue.KeywordsMultiple Sclerosis, fatigue, relapse, autonomic dysfunctions, vagal afferents
Source: Multiple Sclerosis and Related Disorders - Category: Neurology Source Type: research