Impact of hypertension on cerebral microvascular structure in CPAP-treated obstructive sleep apnoea patients: a diffusion magnetic resonance imaging study
ConclusionBased on IVIM analysis, cerebral microvascular structure and function showed no difference between hypertensive and normotensive patients with moderate-to-severe OSA treated with CPAP. Treatment adherence with antihypertensive drug regime and, in turn, controlled hypertension seems not to affect microvascular structure and perfusion of the brain.Trial registrationClinicalTrials.gov Identifier: NCT02493673
I keep hearing radio ads about high-tech cleaners for continuous positive airway pressure (CPAP) machines, which are used to treat sleep apnea. Bacteria and mold can accumulate in different parts of the device. Just the touch of a button, say the ads, and all undesirable organisms lurking in the CPAP pump, tube, and mask will be zapped into oblivion. Your CPAP system will be sanitized and ready for use while you sleep. But can a CPAP system really lead to illness? And if so, do we need space-age technology to clean a CPAP machine? Wait: What is a CPAP system and why is one needed? A CPAP machine is one of the best treatmen...
Fitbit or Apple Watch for running? Garmin or Misfit for swimming? Sleep Cycle or Sleep as Android for sleep tracking? What about measuring heart rate, blood pressure, or tracking how to cut out stress from your life? Dozens of gadgets on the healthcare wearable market promise you a healthier lifestyle, but it’s easy to go astray in the jungle of digital health gadgets. Let me show you my top choices when it comes to health wearables and trackers. Guidance in the health wearable universe By now, I have tested and used more than a hundred devices and gadgets that measure health parameters or vital signs. Thus,...
ConclusionIn this pilot study, through the use of early ABPM we found high rates of non-dipping nocturnal BP in patients following stroke, particularly in those with underlying atrial fibrillation. The availability of 24-hour BP might allow for more individualised antihypertensive management particularly at this high-risk acute stage. Furthermore the presence of abnormal circadian patterns might be a marker for conditions such as atrial fibrillation and obstructive sleep apnoea that compound stroke risk.
CONCLUSIONS: The relationship between OSAS and ischaemic stroke is evident. The advance in the identification of molecular markers and low-cost studies for the identification of OSAS will allow implementing strategies to reduce their consequences in cardiovascular diseases, mainly in ischaemic stroke. PMID: 31497870 [PubMed - in process]
Conclusions: OSA is associated with many diseases seen in neuro-ophthalmology clinics. More studies are required to assess the real ability of CPAP to reverse pathological changes. Ophthalmologists can screen for undiagnosed OSA in patients presenting with certain eye diseases.
This study, the first large scale screening for OSA in Poland, shows a substantial, much higher than previously appreciated, prevalence of risk for OSA in the population at large. PMID: 31372855 [PubMed - as supplied by publisher]
This article aims to summarise the effects of IH on adipose tissue in experimental models in a comprehensive way. Data from well-designed controlled trials are also reported with the final goal of proposing new avenues for improving phenotyping and personalised care in OSA. PMID: 31243096 [PubMed - in process]
This article aims to summarise the effects of IH on adipose tissue in experimental models in a comprehensive way. Data from well-designed controlled trials are also reported with the final goal of proposing new avenues for improving phenotyping and personalised care in OSA.
Obstructive sleep apnea (OSA) is a disorder characterized by breathing cessation caused by obstruction of the upper airway during sleep. It is associated with multiorgan comorbidities such as obesity, hypertension, heart failure, arrhythmias, diabetes mellitus, and stroke. Patients with OSA have an increased prevalence of ophthalmic disorders such as cataract, glaucoma, central serous retinopathy (detachment of retina, macular hole), eyelid laxity, keratoconus, and nonarteritic anterior ischemic optic neuropathy; and some might require surgery.
The underreporting may contribute to the underdiagnosis in women of obstructive sleep apnea, which can lead to high blood pressure, stroke and other health issues.