Strain-specific differences in survival of Campylobacter spp. in naturally contaminated turkey feces and water.

Strain-specific differences in survival of Campylobacter spp. in naturally contaminated turkey feces and water. Appl Environ Microbiol. 2019 Sep 13;: Authors: Good L, Miller WG, Niedermeyer J, Osborne J, Siletzky RM, Carver D, Kathariou S Abstract Campylobacter jejuni and C. coli are leading causes of human foodborne illness with poultry as a major vehicle. Turkeys are frequently colonized with Campylobacter but little is known about Campylobacter survival in turkey feces, even though fecal droppings are major vehicles for Campylobacter within-flock transmission as well as for environmental dissemination. Our objective was to examine survival of Campylobacter, including different strains, in freshly-excreted feces from naturally-colonized commercial turkey flocks and in suspensions of turkey feces in water from the turkey house. Fecal and water suspensions were stored at 4°C and Campylobacter populations were enumerated on selective media at 48-h intervals. C. jejuni and C. coli isolates were characterized for resistance to a panel of antibiotics and a subset was subtyped by multilocus sequence typing. Campylobacter was recovered from feces and water for up to 16 days. Analysis of 548 isolates (218 C. jejuni and 330 C. coli) revealed that C. jejuni survived longer than C. coli in feces (p = 0.0005), while the reverse was observed in water (p
Source: Applied and Environmental Microbiology - Category: Microbiology Authors: Tags: Appl Environ Microbiol Source Type: research

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ConclusionThe study highlights the importance of regular surveillance programs, an efficient infection control program, strict adherence to antiseptic measures and use of a rational antibiotic policy for the early diagnosis and better management of CRBSI.
Source: Medical Journal Armed Forces India - Category: General Medicine Source Type: research
Publication date: December 2019Source: Microbial Pathogenesis, Volume 137Author(s): Sadeq Abdulridha Gatea Kaabi, Hadeel Kareem MusaferAbstractA minimum lethal dose on mice for five bacterial pathogens were identified with PCR of neonatal septicemia of Escherichia coli, Klebsiella pneumoniae, Haemophilus influenzae, Pseudomonas aeruginosa, Citrobacter freundii and Moraxella catarrhalis were studied. Bacteriophage preparations active against 10 isolates of E. coli, 10 isolates of K. pneumoniae, 4 isolates of H. influenzae, 3 isolates of P. aeruginosa, 1 isolate of C. freundii and 1 isolate of M. catarrhalis were tested for ...
Source: Microbial Pathogenesis - Category: Infectious Diseases Source Type: research
ConclusionThe draft genome sequence reported here will lay the foundation for future research on antimicrobial resistance and pathogenic mechanisms in K. quasipneumoniae subsp. quasipneumoniae and also will promote comparative analysis with genomic features among different sources of clinically important multidrug-resistant strains.
Source: Journal of Global Antimicrobial Resistance - Category: Infectious Diseases Source Type: research
ConclusionIt is concluded that NIT resistance in the studied NIT-RE. coli isolates was mainly mediated by nfsA and nfsB alterations.
Source: Journal of Global Antimicrobial Resistance - Category: Infectious Diseases Source Type: research
ConclusionOur findings suggest that curcumin has potential as an anticlostridial agent. More work is needed to further investigate the efficacy of curcumin as a standalone drug or as a supplement of current drugs of choice, as it has no antagonistic activities but might overcome their drawbacks.
Source: Journal of Global Antimicrobial Resistance - Category: Infectious Diseases Source Type: research
Authors: Bassetti M, Giacobbe DR, Peghin M, Irani P Abstract Introduction: Antimicrobial resistance poses a substantial threat to global public health concern, since it decreases the probability of effectively treating an infection and increases risk of morbidity and mortality. Areas covered: In this review, the authors discuss the advantages and disadvantages of classical and novel trial designs for evaluating novel antibiotics for infections due to multidrug-resistant organisms (MDRO). An inductive literature search was performed using different keywords pertinent to the reviewed topics. Expert opinion: The need ...
Source: Expert Review of Clinical Pharmacology - Category: Drugs & Pharmacology Tags: Expert Rev Clin Pharmacol Source Type: research
The objectives of this article are to review key aspects of the epidemiology of T. callipaeda, summarise animal and human cases in Europe and emphasise the importance of education and awareness among veterinarians, physicians (particularly ophthalmologists) and animal, in order to owners to tackle this zoonosis.Graphical Abstract
Source: Veterinary Parasitology - Category: Veterinary Research Source Type: research
In conclusion, our data show a risk for human infection with T. gondii due to consumption of chicken and turkey meat.
Source: Veterinary Parasitology - Category: Veterinary Research Source Type: research
In this study, we showed that expression of the cellular miRNA gga-miR-455-5p was downregulated in vivo and in vitro in response to NDV infection. Next, we found that the transfection of chicken embryonic fibroblasts (CEFs) with gga-miR-455-5p suppressed NDV replication, while the blockade of endogenous gga-miR-455-5p expression with inhibitors enhanced NDV replication. In addition, gga-miR-455-5p enhanced the expression of type I interferon and the interferon-inducible genes (ISGs) OASL and Mx1 by targeting SOCS3, a negative regulator of type I IFN signaling. Altogether, these findings highlight the crucial role of gga-mi...
Source: Veterinary Microbiology - Category: Veterinary Research Source Type: research
Author Affiliations open 1Center for Disease Dynamics, Economics &Policy, Washington, DC, USA 2Public Health Foundation of India, New Delhi, Delhi, India 3Dept. of Veterinary Population Medicine, University of Minnesota, St. Paul, Minnesota, USA 4School of Public Health and Zoonoses, Guru Angad Dev Veterinary and Animal Sciences University, Ludhiana, Punjab, India 5Dept. of Ecology and Evolutionary Biology, Princeton University, Princeton, New Jersey, USA 6SRL Diagnostics, FORTIS Hospital, Noida, Uttar Pradesh, India 7SRL Diagnostics, Mumbai, Maharashtra, India 8Veterinary &Animal Husbandry Extension, Guru Angad D...
Source: EHP Research - Category: Environmental Health Authors: Tags: Research Source Type: research
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