Pharmacokinetics and safety of neratinib during co-administration with loperamide in healthy subjects

ConclusionsNeratinib administered alone and concomitantly with multiple oral doses of loperamide is generally safe and well tolerated. Loperamide has minimal effects on neratinib pharmacokinetic parameters.
Source: Cancer Chemotherapy and Pharmacology - Category: Cancer & Oncology Source Type: research