Antiplatelet strategy after transcatheter aortic valve replacement: an updated meta-analysis.

CONCLUSIONS: The updated meta-analysis presents the evidence that post-TAVR DAPT increases bleeding events, with no benefit in survival and ischemic events, in comparison with SAPT. Nevertheless, it is currently difficult to evaluate by a meta-analysis the effectiveness of DAPT versus SAPT to prevent the valve thrombosis resulting in leaflet dysfunction , due to a limited number of existing publication. Additional RCTs are needed to determine the optimal antiplatelet strategy after TAVR.
PMID: 31486613 [PubMed - as supplied by publisher]

Source: The Journal of Cardiovascular Surgery - September 2, 2019 Category: Cardiovascular & Thoracic Surgery Authors: Ma X, Xu Z, Li J, Zhao D, Kong X, Ma J, Ma H, Yun Y, Sun L, Zhang Y, Wei D, Jiao Q, Zou C, Wang Z Tags: J Cardiovasc Surg (Torino) Source Type: research