Meningitis vaccines in children: what have we achieved and where next?

Purpose of review This review highlights the recent impacts of vaccines against the major bacterial causes of meningitis in children, and the challenges for further prevention of bacterial meningitis, with a focus on Streptococcus pneumoniae, Neisseria meningitidis and group B Streptococcus. Recent findings Conjugate vaccines against S. pneumoniae and N. meningitidis have resulted in dramatic reductions in bacterial meningitis globally where they have been used. Recent licensure and use of capsular group B meningococcal protein vaccines have further reduced meningococcal meningitis in infants, young children and adolescents for countries with endemic disease and during outbreaks. Summary Existing vaccines to prevent bacterial meningitis in children should be utilized in countries with significant numbers of cases of pneumococcal and/or meningococcal meningitis. Vaccines, which are able to protect against more than 13 serotypes of S. pneumoniae are in clinical trials and should be able to further reduce pneumococcal meningitis cases. Cost effective meningococcal vaccines against non-A capsular groups are needed for low-resource countries. There remains an urgent need for a vaccine against group B Streptococcus, which is a major cause of neonatal meningitis globally and for which no vaccine currently exists.
Source: Current Opinion in Infectious Diseases - Category: Infectious Diseases Tags: PAEDIATRIC AND NEONATAL INFECTIONS: Edited by Saul N. Faust Source Type: research

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Publication date: Available online 9 October 2020Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Manuel Jorge Rial, Marcela Valverde, Victoria del Pozo, Francisco Javier González-Barcala, Carlos Martínez-Rivera, Xavier Muñoz, José María Olaguibel, Vicente Plaza, Elena Curto, Santiago Quirce, Pilar Barranco, Javier Domínguez-Ortega, Joaquin Mullol, César Picado, Antonio Valero, Irina Bobolea, Ebymar Arismendi, Paula Ribó, Joaquín Sastre
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research
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Source: NYT - Category: American Health Authors: Tags: your-feed-science Coronavirus Risks and Safety Concerns Food and Drug Administration Hahn, Stephen M (1960- ) Coronavirus (2019-nCoV) Vaccination and Immunization Clinical Trials Drugs (Pharmaceuticals) your-feed-health your-feed-healthc Source Type: news
The use of an immune-system stimulant harvested from shark liver oil in the development of some coronavirus vaccines has animal conservationists pressing for alternatives.(Image credit: Reinhard Dirscherl/ullstein bild via Getty Images)
Source: NPR Health and Science - Category: Consumer Health News Authors: Source Type: news
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Source: Evidence-based Complementary and Alternative Medicine - Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research
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Source: Evidence-based Complementary and Alternative Medicine - Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research
Phoenix Children ’s Hospital held its fourth annual flu POD (point of distribution) this week, with this year's 13-hour blitz holding a special significance amid the global Covid-19 pandemic. On Oct. 7, nurses began vaccinating employees at 6 a.m. and concluded the one-day event at 7 p.m., vaccinating nearly 5,00 0 people. It’s preparation for another potential mass vaccination event: distribution of a safe and effective vaccine for Covid-19. Click through the photo gallery above to see scenes…
Source: bizjournals.com Health Care:Biotechnology headlines - Category: Biotechnology Authors: Source Type: news
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Source: Guardian Unlimited Science - Category: Science Authors: Tags: Coronavirus outbreak Infectious diseases Science World news France Trump administration Donald Trump Source Type: news
Phoenix Children ’s Hospital held its fourth annual flu POD (point of distribution) this week, with this year's 13-hour blitz holding a special significance amid the global Covid-19 pandemic. On Oct. 7, nurses began vaccinating employees at 6 a.m. and concluded the one-day event at 7 p.m., vaccinating nearly 5,00 0 people. It’s preparation for another potential mass vaccination event: distribution of a safe and effective vaccine for Covid-19. Click through the photo gallery above to see scenes…
Source: bizjournals.com Health Care News Headlines - Category: Health Management Authors: Source Type: news
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Source: The Economic Times Healthcare and Biotech News - Category: Pharmaceuticals Source Type: news
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