Deteriorated functional and structural brain networks and normally appearing functional –structural coupling in diabetic kidney disease: a graph theory-based magnetic resonance imaging study

ConclusionDKD patients showed enhanced functional and structural brain network disruption and normally appearing functional –structural coupling compared with DM patients, which correlated with kidney function, renal toxins, and cognitive performance.Key Points• DKD patients showed markedly disrupted functional and structural brain network efficiency measures compared with DM patients and healthy controls.• Reduced kidney function clearly deteriorated functional and structural brain networks in DKD patients.• DKD patients displayed normally appearing functional–structural coupling compared with DM patients.
Source: European Radiology - Category: Radiology Source Type: research