Enhanced xeno-free differentiation of hiPSC-derived astroglia applied in a blood –brain barrier model

ConclusionOur results suggest that astroglia differentiated on LN521 display an improved phenotype and are suitable for coculture in a hiPSC-derived BBB model. This provides a starting point for a more defined and robust derivation of astroglia for use in BBB coculture models.

http://link.springer.com/10.1186/s12987-019-0147-4

Source: Fluids and Barriers of the CNS - August 28, 2019 Category: Neuroscience Source Type: research