Transcriptional Regulation of Epithelial to Mesenchymal Transition Related Genes by Lipopolysaccharide in Human Cervical Cancer Cell Line HeLa.
Conclusion: The
result of this study, LPS is able to reduce E-cadherin expression, caused by increase in repressor E-cadherin protein
expression and some microRNAs, probably. Since bacterial infection can be in cervical site, it is likely to be effective
in reducing the E-cadherin expression in the EMT and enhance cancer process, therefore; removing these infections
by using the appropriate antibiotics may result in slowing down this process, which requires more research.
PMID: 31450920 [PubMed - in process]
Source: Asian Pacific Journal of Cancer Prevention - Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research
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