Emerging role of microRNAs in dilated cardiomyopathy: evidence regarding etiology

Dilated cardiomyopathy (DCM) is a heart muscle disease characterized by ventricular dilation and systolic dysfunction in the absence of abnormal loading conditions or coronary artery disease. This cardiac disorder is a major health problem due to its high prevalence, morbidity and mortality. DCM is a complex disease with a common phenotype but heterogeneous pathological mechanisms. Early etiological diagnosis and prognosis stratification is crucial for the clinical management of the patient. Advances in imaging technology and genetic tests have provided useful tools for clinical practice.

Source: Translational Research - August 22, 2019 Category: Research Authors: Maria Calderon-Dominguez, Thal ía Belmonte, Maribel Quezada-Feijoo, Monica Ramos-Sánchez, Juan Fernández-Armenta, Amparo Pérez-Navarro, Sergi Cesar, Luisa Peña Peña, Àngela Vea, Vicenta Llorente-Cortés, Alipio Mangas, David de Gonzalo-Calvo, Rocio Tags: Review Article Source Type: research