Giant rheumatoid nodule

A 50-year-old female with history of rheumatoid arthritis presented with a large nodule on right medial knee. The lesion had been present for several years and was progressively growing causing her pain. Recently the lesion had begun to ulcerate and drain a yellow liquid. The patient was on methotrexate 20 mg weekly, hydroxychloroquine 200 mg daily, and prednisone 5 mg daily for her rheumatoid arthritis. On her right medial knee, she had a 6.8 cm soft, slightly compressible, yellowish nodule. The lesion was surgically resected under local anesthesia and the defect primarily repaired.
Source: Journal of the American Academy of Dermatology - Category: Dermatology Source Type: research