Prognostic factors and seizure outcome in Posterior Reversible Encephalopathy Syndrome (PRES) in children with hematological malignancies and bone marrow failure: a retrospective monocentric study

Posterior reversible encephalopathy syndrome (PRES), as defined by Hinchey et al. (1996), is a phenomenon of transient cerebral vasogenic edema occurring preferentially in posterior circulation [1]. Clinically, PRES is characterized by headaches, seizures, reduced consciousness, and visual and other focal neurological symptoms [2,3]. PRES is a clinicoradiological syndrome; a characteristic radiologic finding is vasogenic edema in the bilateral parietal-occipital lobes, which might be related to the lower concentrations of sympathetic innervation of the posterior intracranial arteries in comparison with other cerebral regions, resulting in lower autoregulatory capacity in these vessels [4].

Source: Seizure: European Journal of Epilepsy - August 14, 2019 Category: Neurology Authors: Pavl ína Danhofer, Michaela Tomečková, Dáša Černá, Danica Zapletalová, Ondřej Horák, Štefánia Aulická, Lenka Juříková, Jiří Domanský, Petra Kovalčíková, Tomáš Pavlík, Jaroslav Štěrba, Hana Ošlejšková Source Type: research