Induction of ROS and DNA damage-dependent senescence by icaritin contributes to its antitumor activity in hepatocellular carcinoma cells.
Discussion and conclusions: Induction of cellular senescence by ICT defines a novel anticancer mechanism of ICT and provides a rationale for generalizing the study design to a broader study population to further developing ICT as a novel therapeutic agent for treatment of HCC.
PMID: 31407933 [PubMed - in process]
Source: Pharmaceutical Biology - Category: Drugs & Pharmacology Tags: Pharm Biol Source Type: research
More News: Acetylcysteine | Biology | Cancer & Oncology | Carcinoma | Drugs & Pharmacology | Genetics | Hepatocellular Carcinoma | Horny Goat Weed | Liver Cancer | Study