Determining Patient Characteristics Leading to Worse Outcomes with Long Term Milrinone Therapy

Milrinone is an inotrope used in patients with end-stage heart failure awaiting mechanical support, heart transplant or as palliative therapy. Numerous studies have evaluated adverse events and mortality associated with milrinone use, which have shown to be associated with higher mortality rates and arrhythmias. Despite the homogeneous prevalence of these adverse effects, the association of their development with the duration of treatment remains debatable. Additionally, emerging smaller studies have described relative safety of long term milrinone use.
Source: Journal of Cardiac Failure - Category: Cardiology Authors: Tags: 294 Source Type: research