Human Decellularized Dermal Matrix Seeded with Adipose-Derived Stem Cells Enhances Wound Healing in a Murine Model: experimental study

ConclusionGlyaderm® is an effective carrier to deliver ASCs in full-thickness wounds. ASC-seeded Glyaderm® significantly enhances wound healing compared to standard Glyaderm®. The results of this study encourage clinical trials for treatment of full-thickness skin defects. Furthermore, xenogen-free isolation and autologous plasma-augmented culture expansion of ASCs, combined with the existing clinical experience with Glyaderm®, aid in simplifying the necessary procedures in a GMP-laboratory setting.
Source: Annals of Medicine and Surgery - Category: General Medicine Source Type: research