Normalization of ovarian reserve surrogates in a women diagnosed with psoriasis treated with TNF-alpha antagonist. A case report

Introduction: Psoriasis and psoriatic arthritis (PsA) are chronic inflammatory diseases of unclear etiology. There is evidence, that genetic, immunologic, and environmental factors contribute to its pathology. Autoimmune oophoritis has been proposed as one of the possible etiologies of diminished ovarian reserve. Pro-inflammatory cytokine - tumor necrosis factor alpha (TNF α) is implicated in the pathogenesis of oophoritis and psoriasis. Certolizumab is an anti-TNFα monoclonal antibody studied now in the treatment of psoriasis.
Source: Maturitas - Category: Primary Care Authors: Tags: LBP01 Source Type: research