Compartmentalisation of the inflammatory response following aneurysmal subarachnoid haemorrhage.

CONCLUSION: The post aSAH inflammatory response peaks on days 5-7 post ictus and remains largely compartmentalised within the CNS. IL-4 may have a particular association with DIND although its precise role in the pathophysiology of the disorder remains unclear. IL-6 predicted poor outcome but not independently of clinical grade, suggesting that it may be a surrogate marker of early brain injury.
PMID: 31323526 [PubMed - as supplied by publisher]

Source: Cytokine - July 15, 2019 Category: Molecular Biology Authors: Al-Tamimi YZ, Bhargava D, Orsi NM, Teraifi A, Cummings M, Ekbote UV, Quinn AC, Homer-Vanniasinkam S, Ross S Tags: Cytokine Source Type: research