Variants in COL6A3 gene influence susceptibility to esophageal cancer in the Chinese population

Esophageal cancer (EC) is considered a most common gastrointestinal malignant cancer in our world (1). It has a highly morbidity and mortality, more than 450,000 new cases of EC were diagnosed, and about 400,000 patients were died in each year (2). According to histological type, EC was classified two different forms, esophageal squamous cell carcinoma (ESCC) and esophageal adenocarcinoma (EAC) (3). Several reports revealed that ESCC is the main histological subtype of EC in developing countries (4).

Source: Cancer Genetics and Cytogenetics - July 12, 2019 Category: Genetics & Stem Cells Authors: Yang Li, Yao Sun, Qinshuai Yang, Jiamin Wu, Zichao Xiong, Shanqu Li, Tianbo Jin Tags: Original Article Source Type: research