Alteration in memory cognition due to activation of caveolin-1 and oxidative damage in a model of dementia of Alzheimer & #39;s type

CONCLUSION: The findings from the present investigation may conclude that the caveolin-1 from caveolae at the cell membrane induces memory deficits and oxidative stress phenotype that resemble the neurological phenotype of Alzheimer's disease. Further studies are warranted to gauge the effect of caveolin dyshomeostasis on the amyloidogenic cascade.
Source: Indian Journal of Pharmacology - Category: Drugs & Pharmacology Authors: Source Type: research