The effects of thiamine pyrophosphate on ethanol induced optic nerve damage.

CONCLUSIONS: There was an apparent destruction in ethanol administered group in histopathological analyses with an augmented level of oxidative stress markers and all those alterations were prevented with concomitant thiamine pyrophosphate administration. These protective effects of thiamine pyrophosphate are extremely important in chronic ethanol consumption. Clinical studies are warranted to define the exact role of thiamine pyrophosphate in prevention of ethanol induced optic neuropathy. PMID: 31277705 [PubMed - in process]

https://www.ncbi.nlm.nih.gov/pubmed/31277705?dopt=Abstract

Source: BMC Pharmacology and Toxicology - July 8, 2019 Category: Drugs & Pharmacology Tags: BMC Pharmacol Toxicol Source Type: research