HEG1 indicates poor prognosis and promotes hepatocellular carcinoma invasion, metastasis, and EMT by activating Wnt/{beta}-catenin signaling

In conclusion, HEG1 indicates poor prognosis; plays important roles in HCC invasion, metastasis, and EMT by activating Wnt/β-catenin signaling; and can serve as a potentially valuable prognostic biomarker and therapeutic target for HCC.

Source: Clinical Science - July 4, 2019 Category: Biomedical Science Authors: Zhao, Y.-r., Wang, J.-l., Xu, C., Li, Y.-m., Sun, B., Yang, L.-y. Tags: PublishAheadOfPrint Source Type: research