Efficacy and Safety of Brinzolamide as Add-On to Prostaglandin Analogues or β-Blocker for Glaucoma and Ocular Hypertension: A Systematic Review and Meta-Analysis

Conclusions: Brinzolamide, as add-on to PGAs or β-blocker, significantly decrease IOP of patients with refractory glaucoma or OHT and the AEs were tolerable.
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research

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AbstractAplastic anemia (AA) has been reported to be associated with inflammatory bowel disease (IBD), but mostly with ulcerative colitis (UC). Little is known about the associations between AA and Crohn ’s disease (CD). We aim to determine the portraits of patients with AA-CD. Among a total of 657 patients with CD registered in Xijing Hospital of Digestive Diseases IBD center from January 2008 to October 2018, the patients diagnosed with concurrent AA were reviewed. Clinical presentation, medical history, endoscopic features, response to treatment, and prognosis in this set of patients were collected. Six male patie...
Source: Annals of Hematology - Category: Hematology Source Type: research
Conclusions: Since One Shape and Revo-S are both based on the rotational approach and WaveOne on reciprocal approach, less incidence of postoperative pain intensity with One Shape and Revo-S in single-appointment nonsurgical endodontic retreatment could be associated with the motion type during root canal shaping.
Source: Quintessence International - Category: Dentistry Source Type: research
Sk ármeta, Nicolas Patri / Pesce, Maria Cecilia / Saldivia, Josefina / Espinoza-Mellado, Paula / Montini, Francisca / Sotomayor, ClaudioPage 662 - 669Objective: The understanding the etiology of painful temporomandibular disorders (TMD) has evolved over the last eight decades. Evidence-based systematic research had questioned historical concepts and abandoned preconceived dogmas based purely on mechanically based etiologies, transforming TMD into a complex musculoskeletal chronic pain model. Unfortunately, many of these old ideas persist in undergraduate education and the dental community. Revisiting the historical ...
Source: Quintessence International - Category: Dentistry Source Type: research
Publication date: Available online 18 August 2019Source: Journal of Oral Biology and Craniofacial ResearchAuthor(s): Sourav Sarkar, N.T. Prashanth, E.S. Shobha, Vinod Rangan, G. NikhilaAbstractObjectivesThe aim of this study is to compare the effectiveness of Platelet Rich Fibrin gel and Chitosan gel dressing in providing hemostasis in patients receiving Oral Antiplatelet Therapy and also to evaluate their surgical healing outcome following dental extractions.MethodologyA total of 60 patients under Oral Antiplatelet Therapy indicated for tooth extraction were included for treatment in the study without altering the oral an...
Source: Journal of Oral Biology and Craniofacial Research - Category: Dentistry Source Type: research
ConclusionHM might have some beneficial effects including improving insomnia, blood pressure, and mental health, for hypertensive elderly with insomnia. Since the methodological quality of the included studies and QoE were not high, well-designed RCTs are urgent to confirm these results.
Source: European Journal of Integrative Medicine - Category: Complementary Medicine Source Type: research
A Saint Louis University pain researcher has received a $2.1 million grant from the National Institutes of Health to investigate a pain signaling pathway in order to help open up a new avenue for pain medication research, officials said. Dr. Daniela Salvemini has spent her career studying chronic neuropathic pain in order to help find new ways to treat it without opioids. Neuropathic pain affects between 15 and 20 million people in the U.S. This type of pain happens after injuries to the nervous…
Source: bizjournals.com Health Care:Biotechnology headlines - Category: Biotechnology Authors: Source Type: news
PURPOSE: Hydrocodone, codeine, oxycodone, and tramadol are frequently prescribed to adolescents for moderate pain related to minor trauma or dental, surgical, or medical procedures. Pharmacokinetic and pharmacodynamic differences between these opioids coul...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
We describe a case of lormetazepam addiction in a femal...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
HIGH blood pressure is a common condition that can lead to serious and even life-threatening health complications if left untreated. But one of the best ways to avoid these complications and keep blood pressure under control is by making healthy food swaps. So what ’s the best food to eat for breakfast?
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
In an Appalachian town, an unlikely group of activists recognized the early stages of the deadly drug epidemic, and fought in vain to stem its rise.
Source: NYT Health - Category: Consumer Health News Authors: Tags: your-feed-science Opioids and Opiates Pain-Relieving Drugs Drug Abuse and Traffic Drugs (Pharmaceuticals) Nuns OxyContin (Drug) Purdue Pharma Virginia Pennington Gap, Va. Sister Beth Davies Dr. Art Van Zee Sue Ella Kobak Source Type: news
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