MiR-130a exerts neuroprotective effects against ischemic stroke through PTEN/PI3K/AKT pathway.

CONCLUSIONS: Our data demonstrated that miR-130a prevented cerebral I/R damage by mediating the PTEN/PI3K/AKT axis. These preliminarily findings furthered our understanding of this mechanism and identified new potential therapeutic targets for ischemic stroke. PMID: 31226635 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31226635?dopt=Abstract

Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - June 17, 2019 Category: Drugs & Pharmacology Authors: Zheng T, Shi Y, Zhang J, Peng J, Zhang X, Chen K, Chen Y, Liu L Tags: Biomed Pharmacother Source Type: research