Vitamin C kills thyroid cancer cells through ROS-dependent inhibition of MAPK/ERK and PI3K/AKT pathways via distinct mechanisms

Conclusions: Our data demonstrate that vitamin C kills thyroid cancer cells by inhibiting MAPK/ERK and PI3K/AKT pathways via a ROS-dependent mechanism and suggest that pharmaceutical concentration of vitamin C has potential clinical use in thyroid cancer therapy.

Source: Theranostics - June 13, 2019 Category: Molecular Biology Authors: Xi Su, Zhen Shen, Qi Yang, Fang Sui, Jun Pu, Jingjing Ma, Sharui Ma, Demao Yao, Meiju Ji, Peng Hou Tags: Research Paper Source Type: research