Exogenous H2S reduces acetylation levels of mitochondrial respiratory enzymes via regulating NAD+-SIRT3 pathway in cardiac tissues of db/db mice.

CONCLUSION: We conclude that exogenous H2S plays a critical role in improving cardiac mitochondrial function in diabetes by upregulating SIRT3.
PMID: 31184932 [PubMed - as supplied by publisher]

Source: American Journal of Physiology. Endocrinology and Metabolism - June 10, 2019 Category: Physiology Authors: Sun Y, Teng Z, Sun X, Zhang L, Chen J, Wang B, Lu F, Liu N, Yu M, Peng S, Wang Y, Zhao D, Zhao Y, Ren H, Cheng Z, Dong S, Lu F, Zhang W Tags: Am J Physiol Endocrinol Metab Source Type: research