The relationship between chronic obstructive pulmonary disease and non ‐small cell lung cancer in the elderly
The objective of this study was to compare survival between NSCLC patients with and without COPD.MethodsMedical records were retrospectively collected from 301 elderly patients pathologically diagnosed with NSCLC from the Chinese PLA General Hospital. Ultimately, a total of 200 patients were enrolled in the analysis. The survival rates between the COPD ‐NSCLC and non‐COPD NSCLC were assessed using log‐rank and Cox proportional hazard regression analyses.ResultsA total of 117 COPD ‐NSCLC and 93 non‐COPD NSCLC patients were enrolled in the analysis. The median overall survival times were 108.5 months in the non‐COPD group and 45.0 months in the COPD group (HR: 2.05; 95% CI, 1.36‐2.97,P = 0.0004). After 118 patients underwent propensity score matching, the median overall survival times were 100.6 months in the non‐COPD group and 51.9 months in the COPD group (HR: 1.59; 95% CI, 1.096‐2.64,P = 0.0459). The multivariate analysis showed that presence of COPD (HR 1.619,P = 0.030), old age (HR 1.007,P
ConclusionHigh levels of lifestyle-related cancer-risk behaviors were found in most of the Hong Kong construction workers studied. The present study contributes to understanding how cancer-related lifestyle risk behaviors cluster among construction workers and relative impact factors of risk behaviors. It is essential to tailor health behavior interventions focused on multiple risk behaviors among different groups for further enlarging the effects on cancer prevention.
We report one case, in which the patient presented to the emergency department with lower urinary tract symptoms, fever and consumptive syndrome. Acute prostatitis was initially suspected, but subsequently prostate adenocarcinoma was diagnosed.This case enables us to consider the possibility of prostate adenocarcinoma as the diagnose in patients with fever of unknown origin, and the role of procalcitonin to rule out the presence of infection.
Publication date: Available online 21 January 2020Source: European UrologyAuthor(s): Charalampos Fragkoulis, Georgios Papadopoulos, Konstantinos Ntoumas
Publication date: Available online 21 January 2020Source: European UrologyAuthor(s): Jae Heon Kim, In Gab Jeong
Publication date: Available online 21 January 2020Source: European UrologyAuthor(s): Chang Wook Jeong, Samuel L. Washington, Annika Herlemann, Scarlett L. Gomez, Peter R. Carroll, Matthew R. CooperbergAbstractBackgroundActive surveillance (AS)/watchful waiting (WW) strategy for localized prostate cancer (PCa) is increasingly and broadly endorsed as a preferred option for initial treatment of men with very low- and low-risk PCa, but outcomes can be difficult to analyze in traditional, population-based registries. The recently released Surveillance, Epidemiology, and End Results (SEER) Prostate with WW dataset provides an op...
As China has become more attractive for foreigners to travel or work, some Chinese-English bilingual guide signs have been adopted on the highways for the convenience of foreign drivers. This research examined the effectiveness of Chinese-English bilingual...
The remotely sensed burned area (BA) products can provide continuous and spatiotemporally explicit characteristics of fire patches, which are critical data sources for understanding regional fire regimes. However, their accuracy remains to be improved. In ...
ConclusionsElderly patients had the same management as young patients, with no difference in surgery or survival, but with an increase in early loss of autonomy.
Publication date: Available online 22 January 2020Source: European Journal of Surgical OncologyAuthor(s): Isacco Montroni, Nicole M. Saur
ConclusionIn this experimental model, combined therapy with chemotherapy and Adv-shPGK1 improves control of PM of gastric origin as compared to chemotherapy alone and might counteract chemoresistance of PM. A systemic toxicity of Adv-shPGK1 cannot be excluded.