Effects of light on aging and longevity.

Effects of light on aging and longevity. Ageing Res Rev. 2019 May 30;:100913 Authors: Shen J, Tower J Abstract Increasing evidence suggests an important role for light in regulation of aging and longevity. UV radiation is a mutagen that can promote aging and decrease longevity. In contrast, NIR light has shown protective effects in animal disease models. In invertebrates, visible light can shorten or extend lifespan, depending on the intensity and wavelength composition. Visible light also impacts human health, including retina function, sleep, cancer and psychiatric disorders. Possible mechanisms of visible light include: controlling circadian rhythms, inducing oxidative stress, and acting through the retina to affect neuronal circuits and systems. Changes in artificial lighting (e.g., LEDs) may have implications for human health. It will be important to further explore the mechanisms of how light affects aging and longevity, and how light affects human health. PMID: 31154014 [PubMed - as supplied by publisher]
Source: Ageing Research Reviews - Category: Genetics & Stem Cells Authors: Tags: Ageing Res Rev Source Type: research

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Purpose of review Obstructive sleep apnea (OSA) has been recognized as a risk factor for cancer mainly through hypoxia, based on studies that did not distinguish among cancer types. The purpose of this review is to discuss the most recent data on epidemiology and pathophysiology of the OSA–cancer association. Recent findings According to epidemiological studies, OSA may have different influences on each type of cancer, either increasing or decreasing its incidence and aggressiveness. Time spent with oxygen saturation below 90% appears the polysomnographic variable most strongly associated with unfavorable effect...
Source: Current Opinion in Pulmonary Medicine - Category: Respiratory Medicine Tags: SLEEP AND RESPIRATORY NEUROBIOLOGY: Edited by Lee Brown and Winfried Johannes Randerath Source Type: research
CONCLUSIONS: Our study demonstrated that IH and gut microbiota of patients with OSAS activated HIF-1α expression and STAT3 pathway in IMCE cells, with no influence on β-catenin pathway, which suggested that IH, STAT3 pathway, chronic inflammation, and intestinal microbiota dysbiosis may be involved in CRC carcinogenesis correlated with OSAS These findings must be interpreted cautiously and further research is necessary to clarify the causative steps in CRC development. PMID: 33029691 [PubMed - as supplied by publisher]
Source: Sleep and Breathing - Category: Sleep Medicine Authors: Tags: Sleep Breath Source Type: research
ConclusionsOur study demonstrated that IH and gut microbiota of patients with OSAS activated HIF-1 α expression and STAT3 pathway in IMCE cells, with no influence on β-catenin pathway, which suggested that IH, STAT3 pathway, chronic inflammation, and intestinal microbiota dysbiosis may be involved in CRC carcinogenesis correlated with OSAS These findings must be interpreted cautiously and furth er research is necessary to clarify the causative steps in CRC development.
Source: Sleep and Breathing - Category: Respiratory Medicine Source Type: research
ConclusionsThe study results suggest that patients with high risk for OSA have a tendency to develop postoperative wound complications after breast cancer surgery. This study lays groundwork for further scrutiny using more robust methodology.
Source: Sleep and Breathing - Category: Respiratory Medicine Source Type: research
Analyze the effects of a 12-week dance intervention on the sleep quality and the level of pain among women with breast cancer.
Source: Journal of Bodywork and Movement Therapies - Category: Physiotherapy Authors: Tags: Prevention and Rehabilitation Source Type: research
In this issue of the Journal, a group of distinguished Nordic researchers, led by Anne Helene Garde and including four of our Associated Editors, present a discussion paper that originated from a workshop and provides detailed recommendations on night shift work (1). The recommendations are very clear: to protect workers ’ health, night shift schedules should have: (i) ≤3 consecutive night shifts; (ii) shift intervals of ≥11 hours; and (iii) ≤9 hours shift duration. For pregnant women, night work should be limited to one shift per week. The authors acknowledge that under circumstances allowing better possibi...
Source: Scandinavian Journal of Work, Environment and Health - Category: Occupational Health Tags: Editorial Source Type: research
(Natural News) Sleep is an important component of good health. It promotes healing and prepares the body for the next day, among other functions. That said, there are adverse consequences to lack of sleep, and a recent study shows just how grave they can be. A group of researchers from Pennsylvania State University found that people with diabetes,...
Source: NaturalNews.com - Category: Consumer Health News Source Type: news
Who do you think understands more about bipolar disorder: a psychiatrist or a patient with the illness? In this Not Crazy podcast, we discuss whether a patient can be considered a mental health expert without all the credentials after their name. Today we invite writer and bipolar advocate Natasha Tracy — who also has bipolar disorder — to the show to give her opinion. Would you seek advice from a patient? Join us for an in-depth discussion on mental health patients as experts. (Transcript Available Below) Subscribe to Our Show! And Please Remember to Rate &Review Us!   Guest Information for &lsquo...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: General Interview Not Crazy Podcast Policy and Advocacy Source Type: blogs
Who do you think understands more about bipolar disorder: a psychiatrist or a patient with the illness? In this Not Crazy podcast, we discuss whether a patient can be considered a mental health expert without all the credentials after their name. Today we invite writer and bipolar advocate Natasha Tracy — who also has bipolar disorder — to the show to give her opinion. Would you seek advice from a patient? Join us for an in-depth discussion on mental health patients as experts. (Transcript Available Below) Subscribe to Our Show! And Please Remember to Rate &Review Us!   Guest Information for &lsquo...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: General Interview Not Crazy Podcast Policy and Advocacy Source Type: blogs
Conclusions: Although larger studies are needed to confirm these results, our data open up new ways of investigation into the effects of AIs on QoL in HR+ BC patients.Oncology
Source: Oncology - Category: Cancer & Oncology Source Type: research
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