Copper(II)-dependent hydrolysis of trichloronate by turkey serum albumin

This study aims at characterizing the trichloronate enantiomers hydrolysis by serum and albumin from chicken (CSA) and turkey (TSA) in the presence of copper by chiral chromatography. A significant Cu2+-dependent hydrolysis for both trichloronate enantiomers (38%) was observed in turkey serum and TSA (p 
Source: Chemico Biological Interactions - Category: Biochemistry Source Type: research

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Publication date: Available online 7 January 2020Source: Journal of Herbal MedicineAuthor(s): Sophida Sukprasert, Kanoktip Pansuksan, Kusuma SriyakulAbstractThe leaves and stems of Lysiphyllum strychnifolium (Craib) A. Schmitz (Fabaceae family) have been traditionally used in Thailand for detoxification and to treat pesticide poisoning in humans. To uncover novel uses of L. strychnifolium, the possible antiviral properties against avian influenza virus A, strain H5N1, were explored in this study. The ethanolic extracts of L. strychnifolium leaves and stems showed good inhibitory activities against H5N1 neuraminidase. Such ...
Source: Journal of Herbal Medicine - Category: Complementary Medicine Source Type: research
Foods may potentially serve as vehicles for the transmission of antimicrobial-resistant variants of Staphylococcus aureus that are important in a human clinical context. Further, retail food products can be a cause of staphylococcal food poisoning. For these reasons and to account for source attribution and risk assessment, detailed information on the population structure, resistance, and virulence profiles of S. aureus originating from retail food products is necessary. In the current study, whole-genome sequences from 88 S. aureus isolates were subjected to bioinformatics analyses in relation to sequence types, antimicro...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
Publication date: Available online 19 October 2019Source: Comparative Biochemistry and Physiology Part C: Toxicology &PharmacologyAuthor(s): Shouta M.M. Nakayama, Ayuko Morita, Yoshinori Ikenaka, Yusuke K. Kawai, Kensuke P. Watanabe, Chihiro Ishii, Hazuki Mizukawa, Yared B. Yohannes, Keisuke Saito, Yukiko Watanabe, Masaki Ito, Natsuo Ohsawa, Mayumi IshizukaAbstractWorldwide use of anticoagulant rodenticides (ARs) for rodents control has frequently led to secondary poisoning of non-target animals, especially raptors. In order to suggest some factors that may help considering the mechanism of the incidents, this study fo...
Source: Comparative Biochemistry and Physiology Part C: Toxicology and Pharmacology - Category: Toxicology Source Type: research
Abstract Worldwide use of anticoagulant rodenticides (ARs) for rodents control has frequently led to secondary poisoning of non-target animals, especially raptors. In order to suggest some factors that may help considering the mechanism of the incidents, this study focused on the avian vitamin K 2, 3-epoxide reductase (VKOR) that is the target protein of ARs. We addressed the interspecific differences in VKOR activity and inhibition related to amino acid sequence and mRNA expression of VKORC1 and VKORC1-like1 (VKORC1L1). Poultry have been considered to be more tolerant to ARs than mammals. However, VKOR activity o...
Source: Comparative biochemistry and physiology. Toxicology and pharmacology : CBP - Category: Biochemistry Authors: Tags: Comp Biochem Physiol C Toxicol Pharmacol Source Type: research
We examined 9293 individuals from the Copenhagen General Population Study using nuclear magnetic resonance spectroscopy measurements of total cholesterol, free- and esterified cholesterol, triglycerides, phospholipids, and particle concentration. Fourteen subclasses of decreasing size and their lipid constituents were analysed: six subclasses were very low-density lipoprotein (VLDL), one intermediate-density lipoprotein (IDL), three low-density lipoprotein (LDL), and four subclasses were high-density lipoprotein (HDL). Remnant lipoproteins were VLDL and IDL combined. Mean nonfasting cholesterol concentration was 72...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Abstract Patterns of lead and other trace metals were examined in 122 Eurasian eagle owls Bubo bubo found dead in Sweden in the period 1978-2013. Environmental lead (Pb) has decreased over recent decades from reduced anthropogenic emissions but mortality by Pb poisoning is still frequently reported for avian raptors and scavengers exposed to Pb ammunition. One objective here was to determine if Pb concentrations in a nocturnal non-scavenging raptor follow the general decline observed in other biota. Pb concentration in owl liver was significantly correlated with body weight, sex, latitude, longitude and season. Pb...
Source: Archives of Environmental Contamination and Toxicology - Category: Environmental Health Authors: Tags: Arch Environ Contam Toxicol Source Type: research
This study aims at characterizing the trichloronate enantiomers hydrolysis by serum and albumin from chicken (CSA) and turkey (TSA) in the presence of copper by chiral chromatography. A significant Cu2+-dependent hydrolysis for both trichloronate enantiomers (38%) was observed in turkey serum and TSA (p 
Source: Chemico-Biological Interactions - Category: Molecular Biology Authors: Tags: Chem Biol Interact Source Type: research
This study identified prophages as mediators of bacterial virulence in a model of infectious endocarditis, probably through promotion of interaction with extracellular matrix components. Further studies are needed to identify mechanisms leading to promotion of intrinsic virulence. Introduction Challenges related to Staphylococcus aureus infections in the human and veterinary clinics mobilized important human and technical resources. S. aureus can colonize 20–30% of the general population asymptomatically but is also capable of causing a wide spectrum of diseases ranging from benign infections, to particularly...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
This study provides new insight into the characterization of foodborne C. perfringens and highlights the potential of WGS for the investigation of FBOs. Introduction Clostridium perfringens is a Gram-positive, spore-forming, anaerobic, rod-shaped bacterium, known as an important causative agent of foodborne and non-foodborne gastroenteritis (Grass et al., 2013). The ability of this bacterium to form resistant spores contributes to its survival in many environmental niches, including soil, sewage, foods, and the intestinal microbiota of humans and animals (Xiao, 2014; Li et al., 2016). C. perfringens can cause necro...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
Abstract Lead (Pb) is an environmental pollutant and can damage organisms. Selenium (Se) can alleviate Pb poisoning. The present study aimed to investigate alleviative effect of Se on Pb-caused immune toxicity in chicken hearts. One hundred and eighty Hy-line male chickens were randomly divided into four groups at 7 days of age. The control group was offered a standard commercial diet (SD) and drinking water (DW); the Se group was offered SD supplemented with sodium selenite (SeSD) and DW; the Pb + Se group was offered SeSD and DW supplemented with lead acetate (PbDW); and the Pb group was offered SD...
Source: Avian Pathology - Category: Pathology Authors: Tags: Avian Pathol Source Type: research
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