Radiogenomics in head and neck cancer: correlation of radiomic heterogeneity and somatic mutations in TP53, FAT1 and KMT2D

ConclusionThe landscape of somatic variants in our cohort is well in line with previous reports. An association of somatic mutations inFAT1 with reduced radiomic tumour heterogeneity could potentially elucidate the previously described favourable outcomes of these patients. Larger studies are needed to validate this exploratory data in the future.
Source: Strahlentherapie und Onkologie - Category: Cancer & Oncology Source Type: research