Quality of Life Still Good with HIPEC Surgery for Peritoneal Mesothelioma
This study shows that the improvement in quality of life can be very significant compared with the preoperative status,” Levine said. “By six months, virtually all of the patients had recovered to preoperative baseline or better quality-of-life measures.” The post Quality of Life Still Good with HIPEC Surgery for Peritoneal Mesothelioma appeared first on Mesothelioma Center - Vital Services for Cancer Patients &Families.
Conclusions: Mechanical ventilation leads to down-regulation of R-spondin1. R-spondin1 may enhance the interaction of leucine-rich repeat containing G-protein coupled receptor 5 and apoptosis-stimulating protein of p53 2, thus inactivating p53-mediated proapoptotic pathway in cyclic stretched mouse lung vascular endothelial cells. R-spondin1 may have clinical benefit in alleviating mechanical ventilator-induced lung injury.
Conclusions: The prevalence of long-term posttraumatic stress disorder symptoms among family members of acute respiratory distress syndrome survivors is high. Family members with preexisting mental health disorders, recent experiences of serious physical illness, and family members of previously healthy patients are at increased risk for posttraumatic stress disorder symptoms.
Publication date: Available online 13 June 2019Source: CellAuthor(s): Chien-Hsiang Hsu, Steven J. Altschuler, Lani F. WuSummaryChemotherapy is designed to induce cell death. However, at non-lethal doses, cancer cells can choose to remain proliferative or become senescent. The slow development of senescence makes studying this decision challenging. Here, by analyzing single-cell p21 dynamics before, during, and days after drug treatment, we link three distinct patterns of early p21 dynamics to final cell fate. Surprisingly, while high p21 expression is classically associated with senescence, we find the opposite at early ti...
This study could be beneficial for: (i) Clinicians to receive second opinion from the CAD system for early diagnosis, and (ii) Researchers to analyze and enhance the existing state-of-art techniques used in CAD system, which may further reduce the gap of variability between intra and inter observer.Graphical abstract
MRI studies show multiple sclerosis brain changes linked to depression, but randomized controlled trials of antidepressants in this population are lacking.Medscape Medical News
In this study, we evaluated QOL after HIPEC for peritoneal mesothelioma.MethodsThis was a prospective study performed after HIPEC for peritoneal mesothelioma between 2002 and 2015. Patients completed QOL surveys, including the Short Form-36 (SF-36), Functional Assessment of Cancer Therapy + Colon (FACT-C), Brief Pain Inventory (BPI), and Center for Epidemiologic Studies Depression Scale (CES-D) preoperatively and at 3, 6, 12, and 24 months postoperatively.ResultsOverall, 46 patients underwent HIPEC for peritoneal mesothelioma and completed QOL surveys. Mean age was 52.8 ± 13.8 ...
There is very little information available on the psychological care needs of people with malignant mesothelioma. Even less is known about people who have been exposed to asbestos but do not have mesothelioma. A newly published systematic research review sheds light on the distress people experience in these situations. In March 2018, the American Journal of Industrial Medicine published an article highlighting the need for additional studies. Researchers described what is known about asbestos-affected people and how and why they experience so much mental and emotional distress. Most Affected People Exposed Through Work Th...