Correlation of fluorine 18-labeled sodium fluoride uptake and arterial calcification on whole-body PET/CT in cancer patients

Conclusion Our finding of a weak but significant positive correlation between 18F-NaF uptake and arterial calcification suggests that 18F-NaF PET/CT could provide complementary information of active microcalcification for atherosclerosis evaluation in cancer patients.
Source: Nuclear Medicine Communications - Category: Nuclear Medicine Tags: ORIGINAL ARTICLES Source Type: research

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Publication date: Available online 19 June 2019Source: The Annals of Thoracic SurgeryAuthor(s): Jennifer M. Nishimura, Aliya Z. Ansari, Desmond M. D’Souza, Susan D. Moffatt-Bruce, Robert E. Merritt, Peter J. KneuertzAbstractBackgroundSarcopenia is characterized by loss of skeletal muscle and strength, associated with aging, poor nutrition, sedentary lifestyle and chronic illness. We sought to evaluate the current evidence on the prevalence of sarcopenia assessed by computed tomography (CT) imaging in patients undergoing lung cancer resection and its predictive value for perioperative and long-term outcomes.MethodsWe ...
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research
ConclusionsThis case demonstrates that radiotherapy may be a safe and effective treatment modality through careful monitoring of implantable cardioverter-defibrillators in patients with lung cancer who have implantable cardioverter-defibrillators.
Source: Journal of Medical Case Reports - Category: General Medicine Source Type: research
This study found that Shisa3 was strongly expressed in the calvarial bones of mice, especially in osteoblasts. In addition, adenovirus-mediated gene transfer of murine Shisa3 significantly inhibited Wnt3a-induced nuclear translocation ofβ-catenin and mRNA expression of the Wnt target geneAxin2. In bone phenotype assessments ofShisa3 knockout (Shisa3 KO) mice, micro-computed tomography, mRNA expressions of osteoblast markers, and skeletal preparations all displayed no significant differences compared withShisa3 wild-type mice. mRNA expression analysis of canonical Wnt signaling target genes (Axin2,Lef1,Dkk1, andTnfrsf1...
Source: Journal of Bone and Mineral Metabolism - Category: Orthopaedics Source Type: research
Publication date: Available online 18 June 2019Source: Respiratory Medicine Case ReportsAuthor(s): Daisuke Shibahara, Makoto Furugen, Shiho Kasashima, Kozue Kaneku, Tomoko Yamashiro, Wakako Arakaki, Takuro Ariga, Eriko Atsumi, Hajime Aoyama, Hirofumi Matsumoto, Hiroki Maehara, Jiro FujitaAbstractA 70-year-old Japanese man with stage IV EGFR-mutated lung adenocarcinoma complained of right mild back pain. The patient had been heavily treated with several cytotoxic or molecular targeted agents for 10 years and received a palliative radiation therapy of 2nd sacral vertebra 5 years ago. Computed tomography showed the abnormal l...
Source: Respiratory Medicine Case Reports - Category: Respiratory Medicine Source Type: research
What is a CT Scan? A machine whirs in an arc around a patient, snapping a rapid-fire series of x-rays from different angles. These x-ray snapshots are combined by a computer to produce virtual cross-section images of the body. These are called CT scans, which stands for computed tomography (computer-generated cross-sectional images). CT Scans Compared to Ultrasounds and MRIs When the CT scan was first introduced in the 1970s it caused something of a revolution in medicine, allowing doctors to see the inner structure of the body in a way that had been previously hidden – without surgery. Parents often wonder which is ...
Source: Conversations with Dr Greene - Category: Child Development Authors: Tags: Dr. Greene's Blog CT Scan Safety Top Children's Safety Source Type: blogs
A 90 ‐year‐old woman was admitted to our hospital with suspected lung adenocarcinoma. Preoperative three‐dimensional reconstructed computed tomography revealed displacement of the anterior segmental bronchus (B3) arising from the right middle lobe bronchus with absence of the fissure between the ri ght upper and middle lobes. A complete thoracoscopic right upper lobectomy was successfully performed. It is crucial to identify such anomalies prior to lung resection to avoid intraoperative complications during thoracoscopic lobectomy or segmentectomy. Additionally, intravenous indocyanine green w ith a fluorescence syst...
Source: Thoracic Cancer - Category: Cancer & Oncology Authors: Tags: CASE REPORT Source Type: research
This study reports the findings from 9 sheep that received sensor implantations. Time taken from initial CT scans to the placement of a single sensor into an OPA tumour was 45 ± 5 min, with all implantations resulting in the successful delivery of sensors into tumours. Immediate post-implantation mild pneumothoraces occurred in 4 sheep, which was successfully managed in all cases. This is, to the best of our knowledge, the first description of the use of naturally-occurring OPA cases as a pre-clinical surgical model. Through the integration of techniques used in the treatment of human lung cancer patients, including...
Source: Frontiers in Oncology - Category: Cancer & Oncology Source Type: research
Hodgkin lymphoma (HL) has been the archetype for tumor staging and restaging in oncology[1] with extensive evidence of the high diagnostic accuracy of [18F]-Fluoro-Deoxy-Glucose Positron Emission Tomography (FDG-PET) combined with computed tomography (PET/CT).[2 –4] The exceptional performance of PET/CT in HL results most likely from the peculiar architecture of HL composed of a minority (5%) of neoplastic cells, the Hodgkin and Reed-Sternberg (HRS) cells, embedded in a microenvironment (ME) of non-neoplastic inflammatory/immune cells.
Source: Cancer Treatment Reviews - Category: Cancer & Oncology Authors: Tags: Hot Topic Source Type: research
This study has terrific significance and could be extremely important,” Harbut, clinical professor of internal medicine at Wayne State University and Michigan State University, told The Mesothelioma Center at Asbestos.com. “We’re going after this one with great guns.” The study is part of a new partnership between Owlstone Medical — the Breath Biopsy inventor in the United Kingdom — and the International Association of Heat and Frost Insulators and Allied Workers, a building trade union that covers the United States and Canada. Early Diagnosis Still a Rarity The first part of the study ...
Source: Asbestos and Mesothelioma News - Category: Environmental Health Authors: Source Type: news
To evaluate integrated 2-[18F]-fluoro-2-deoxy-d-glucose (18F-FDG) positron-emission tomography (PET)/magnetic resonance imaging (MRI), in comparison with the standard technique, integrated 18F-FDG-PET/computed tomography (CT), in preoperative staging of oesophageal or gastroesophageal junctional cancer.
Source: Clinical Radiology - Category: Radiology Authors: Source Type: research
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