Haematological, serum biochemical and histopathological changes in hepatitis E virus seropositive pigs in Ibadan, Nigeria

This study evaluated the haematological, serum biochemical and histopathological changes in HEV seropositive pigs. A total of 120 pigs were sourced from the Bodija Municipal abattoir, Ibadan, Nigeria, for this study. The haematology and serum biochemistry of the sampled pigs seropositive to HEV antibodies using the ID Screen ® Hepatitis E Indirect Multi-species ELISA biwell kit were analysed. Liver and spleen samples were also taken for histopathological examination and lesion scoring. HEV seropositivity was reported in 57.5% (69/120) of the pigs and associated with a significant (p 
Source: Comparative Clinical Pathology - Category: Pathology Source Type: research

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AbstractHuman pegivirus 2 (HPgV-2) is a recently recognized pegivirus of the familyFlaviviridae. To investigate the epidemic features of HPgV-2 circulating in the human immunodeficiency virus (HIV)-infected population, we tested for antibodies and viral RNA of HPgV-2 and hepatitis C virus (HCV) with retrospective plasma samples collected from 771 HIV infections with multiple risk behaviors in Honghe Prefecture of Yunnan Province. A total of 195 subjects (25.29%) were seroreactive to HPgV-2, and 41 (5.32%) were RNA positive. Although the positive rate of HPgV-2 antibodies in HIV/HCV-coinfected individuals (27.69%) was signi...
Source: Archives of Virology - Category: Virology Source Type: research
This study included 11 samples that were found positive in HCV RNA detection and HCV Ag-Ab ELISA but negative in HCV antibody detection assays (HCV Ab ELISA and rapid), 10 samples that were found positive in HCV Ag-Ab ELISA and HCV Ab ELISA but negative in HCV Ab Rapid, 69 samples that were found positive in HCV Ag-Ab ELISA, HCV Ab ELISA, and HCV Ab Rapid, and 509 samples that were found negative in HCV Ag-Ab ELISA, HCV Ab ELISA, and HCV Ab Rapid. Three seroconversion panels, PHV 913, PHV 911 (M) and PHV904-00-1.0, and a  HCV RNA genotype qualification panel (2400-0182) acquired from Seracare Life Sciences (USA) were ...
Source: Archives of Virology - Category: Virology Source Type: research
This study aimed to characterize LFTs in a large cohort of participants with acute HIV infection initiating immediate antiretroviral therapy (ART) and examine the association between LFTs and biomarkers of HIV infection and inflammation. METHODS: We measured LFTs at the time of HIV diagnosis and at 4, 12, 24 and 48 weeks after ART initiation in 426 Thai individuals with acute HIV infection from 2009 to 2018. A subset of individuals had data available at 96 and 144 weeks. We excluded individuals with concomitant viral hepatitis. Alanine aminotransferase (ALT) was the primary outcome of interest; values greater...
Source: Journal of the International AIDS Society - Category: Infectious Diseases Tags: J Int AIDS Soc Source Type: research
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Source: AllAfrica News: Pregnancy and Childbirth - Category: OBGYN Source Type: news
Udi-Iva Valley region of Enugu state has the most concentration of landslide in Southeastern Nigeria. Detailed field investigations alongside satellite image studies were employed to delineate nine landslide conditioning factors. Lithology, elevation, slop...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Disaster Preparedness Source Type: news
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Source: Medscape Today Headlines - Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news
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Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news
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