Low Maternal Dietary Folate Alters Retrotranspose by Methylation Regulation in Intrauterine Growth Retardation (IUGR) Fetuses in a Mouse Model.

CONCLUSIONS Maternal dietary folate deficiency impaired one-carbon metabolism, leading to global DNA and LINE-1 hypomethylation, and then increased retrotransposition in fetuses, which can lead to IUGR.
PMID: 31061382 [PubMed - in process]

Source: Medical Science Monitor - May 8, 2019 Category: Research Tags: Med Sci Monit Source Type: research