Evaluation of collagen/hydroxyapatite electrospun layers loaded with vancomycin, gentamicin and their combination: Comparison of release kinetics, antimicrobial activity and cytocompatibility.

In conclusion, COL/HA layers with 15 wt% of HA impregnated with vancomycin or with a combination of vancomycin and gentamicin offer a promising treatment approach and the potential to prevent infection during the joint replacement procedures. PMID: 31055065 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31055065?dopt=Abstract

Source: European Journal of Pharmaceutics and Biopharmaceutics - May 1, 2019 Category: Drugs & Pharmacology Authors: Suchý T, Šupová M, Sauerová P, Hubálek Kalbáčová M, Klapková E, Pokorný M, Horný L, Závora J, Ballay R, Denk F, Sojka M, Vištejnová L Tags: Eur J Pharm Biopharm Source Type: research