Biopsy-proven progressive multifocal leukoencephalopathy in a renal transplant patient.

Biopsy-proven progressive multifocal leukoencephalopathy in a renal transplant patient.
Saudi J Kidney Dis Transpl. 2019 Mar-Apr;30(2):526-530
Authors: Guru PK, Vissing MB, Agarwal A, Krishna M
Abstract
Progressive multifocal leukoencephalopathy (PML) is a rare demyelinating disease that affects immunocompromised hosts. Most often the disease is reported in association with leukemia, lymphoma, and AIDS. With recent advancements in immunosuppressive medications and subsequent rise in solid organ transplantations, it is becoming more prevalent in this population. Both the diagnosis and treatment of PML remains a challenge to the transplant community. The disease remains mostly underreported and undertreated. The diagnostic uncertainty in a renal transplant patient leads us to do the brain biopsy for suspicion and confirmation of PML.
PMID: 31031391 [PubMed - in process]

Source: Saudi Journal of Kidney Diseases and Transplantation - February 28, 2019 Category: Urology & Nephrology Authors: Guru PK, Vissing MB, Agarwal A, Krishna M Tags: Saudi J Kidney Dis Transpl Source Type: research