Balancing the risk and rewards of utilizing organs from hepatitis C viremic donors.
Balancing the risk and rewards of utilizing organs from hepatitis C viremic donors.
Curr Opin Organ Transplant. 2019 Apr 16;:
Authors: Sise ME, Strohbehn IA, Bethea E, Gustafson JL, Chung RT
Abstract
PURPOSE OF REVIEW: Owing to long waitlist times and high waitlist morbidity and mortality, strategies to increase utilization of hepatitis C viremic-deceased donor organs are under investigation in kidney, liver, heart, and lung transplantation.
RECENT FINDINGS: Direct-acting antiviral medications for hepatitis C virus infection have high cure rates and are well tolerated. Small, single-center trials in kidney and heart transplant recipients have demonstrated that with early posttransplant direct-acting antiviral therapy, 100% of uninfected recipients of hepatitis C viremic organs have been cured of infection after transplantation.
SUMMARY: In this manuscript, we review the risks and rewards of utilizing hepatitis C viremic organs for transplantation.
PMID: 31008739 [PubMed - as supplied by publisher]
Source: Current Opinion in Organ Transplantation - Category: Transplant Surgery Authors: Sise ME, Strohbehn IA, Bethea E, Gustafson JL, Chung RT Tags: Curr Opin Organ Transplant Source Type: research
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