Targeting LIF-mediated paracrine interaction for pancreatic cancer therapy and monitoring

Targeting LIF-mediated paracrine interaction for pancreatic cancer therapy and monitoringTargeting LIF-mediated paracrine interaction for pancreatic cancer therapy and monitoring, Published online: 17 April 2019; doi:10.1038/s41586-019-1130-6A systematic proteomic investigation of disease mediators secreted by pancreatic stellate cells identifies leukaemia inhibitory factor (LIF) as a key factor that acts on cancer cells, promoting tumour progression and chemoresistance.

Source: Nature AOP - April 16, 2019 Category: Research Authors: Yu Shi Weina Gao Nikki K. Lytle Peiwu Huang Xiao Yuan Amanda M. Dann Maya Ridinger-Saison Kathleen E. DelGiorno Corina E. Antal Gaoyang Liang Annette R. Atkins Galina Erikson Huaiyu Sun Jill Meisenhelder Elena Terenziani Gyunghwi Woo Linjing Fang Thom P. Source Type: research