Differential impact and heterogeneous needs. A peer-led training program for improving chronic patients' health status and health behaviors.

CONCLUSIONS: The peer training had a positive impact, with differences depending on social profiles. 1-year and 2-years posttest measurements are needed and a qualitative study is required in order to better evaluate the peer-led strategy and to adapt it to participants' needs and expectations. PMID: 30982640 [PubMed - as supplied by publisher]
Source: Atencion Primaria - Category: Primary Care Authors: Tags: Aten Primaria Source Type: research

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ConclusionThus our results showed that higher IL-37 was associated with increased insulin sensitive in elderly type 2 DM patients through suppressing the gut microbiota dysbiosis.
Source: Molecular Immunology - Category: Allergy & Immunology Source Type: research
Publication date: Available online 22 June 2019Source: Neuroscience LettersAuthor(s): Q. Leyrolle, S. Laye, A. NadjarAbstractMicroglia are key players in brain function by maintaining brain homeostasis across lifetime. They participate to brain development and maturation through their ability to release neurotrophic factors, to remove immature synapses or unnecessary neural progenitors. They modulate neuronal activity in healthy adult brains and they also orchestrate the neuroinflammatory response in various pathophysiological contexts such as aging and neurodegenerative diseases. One of the main features of microglia is t...
Source: Neuroscience Letters - Category: Neuroscience Source Type: research
In this study, subcritical water extraction (SWE), SWE in aqueous citric acid (pH 5.0) (SWEC), and ultrasound-assisted SWEC (USWEC) were used to extract soluble dietary fiber (SDF) from wheat bran. Results showed that SWE-based methods significantly influenced the physicochemical, functional, and biological properties of the SDF. The fraction SDF-III attained via USWEC had higher SDF yield (46.30%) and carbohydrate content (82.91%), and lower weight-average molecular weight (65.2 kDa) and particle size (1.17 μm), and looser and more porous surface structure, compared with the SDF-I and SDF-II obtained by SWE and SWE...
Source: Food Chemistry - Category: Food Science Source Type: research
Oral semaglutide, the investigational first oral GLP-1 receptor agonist, could expand currently suboptimal treatment options for patients with type 2 diabetes and moderate renal impairment.Medscape Medical News
Source: Medscape Transplantation Headlines - Category: Transplant Surgery Tags: Diabetes & Endocrinology News Source Type: news
Publication date: 15 October 2019Source: Carbohydrate Polymers, Volume 222Author(s): P. Pramod Kumar, Harish Prashanth K. V.AbstractAcrylamide (AA) presence and formation are predominant in fried, baked and heat-processed foods. Using Drosophila model, we have investigated the dietary AA-arbitrate oxidative stress induced neurotoxicity and the effect of soluble Low Molecular Weight Chitosan (LMWC) supplementation. We assessed the neurodegenerative and behavioural effect of AA (0–10 mM) exposure in Drosophila (adult males). As a result, the exposed flies showed distinctive locomotor impairments and incident of morta...
Source: Carbohydrate Polymers - Category: Biomedical Science Source Type: research
In this study, C57BL/6 J mice were parentally exposed to 100 ppb arsenic before conception. After weaning, both male and female offspring were maintained on 100 ppb arsenic and fed either a normal (LFD) or high fat diet (HFD). At 10 and 24 weeks of age, the offspring were sacrificed and kidneys collected. Exposure to arsenic led to an increase body-weight in LFD diet-fed female but not male mice. This response was not observed in HFD-fed female mice; however male mice showed significant increases in body weight in both As- and non-treated animals. Histological analysis shows that arsenic exposure significantly increa...
Source: Chemico Biological Interactions - Category: Biochemistry Source Type: research
Publication date: Available online 22 June 2019Source: Sensors and Actuators B: ChemicalAuthor(s): Rocio Thea, Diego Onna, Mark P. Kreuzer, Mariana HamerAbstractOne of the main confirmatory metabolites of diabetes mellitus is known as glycosylated hemoglobin (HbA1c), a hemoglobin modified with cis-diol sugars. This work presents an optical detection of this metabolite via the preparation and characterization of glass surfaces coated with gold nanoparticles (AuNPs) and subsequently modified with boronic acid to enhance specificity. Through the localized surface plasmon resonance intrinsic to the AuNPs an absorbance enhancem...
Source: Sensors and Actuators B: Chemical - Category: Chemistry Source Type: research
The first necessity is of course oxygen. Without it you'll die in a couple of minutes. The second is water, without which you'll be lucky to last a week.If you enter " Global Water Crisis " into your favorite Internet search engine, you will get pages of documents with enough information to earn a Ph.D. I actually recommendthe Wikipedia article in this instance, which is very thorough and well presented. It's also very long so you might want to take a look at the more succinct entryat the World Resources Institute. That one is a couple of years old and things have already gotten worse.The fact is that over the pa...
Source: Stayin' Alive - Category: American Health Source Type: blogs
Cardiovascular outcomes trials show beneficial effects of sodium-glucose cotransporter 2 inhibitors (SGLT2i) on both cardiovascular and renal outcomes, sparking renewed interest in cardiorenal syndrome.Medscape Diabetes &Endocrinology
Source: Medscape Critical Care Headlines - Category: Intensive Care Tags: Diabetes & Endocrinology Commentary Source Type: news
Medication side-effects can seem unbearable at times: dry mouth, nausea, dizziness, constipation. Certain prescriptions can also increase our risks for developing chronic conditions like thyroid disease and diabetes. Three years ago, I decided that the pills’ side-effects weren’t worth the relief they brought, so I slowly weaned off all my medication. I then plummeted into a severe depression that ended up taking a far greater toll on my health than the nuisance of my drugs. You may be justifiably concerned about how your mood stabilizer and antidepressant are altering your biochemistry, but also consider the g...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Depression General Medications Antidepressant Cognitive Decline Diabetes Mood Stabilizer Source Type: blogs
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